{"id":"W2060944287","doi":"10.1182/blood-2004-01-0150","title":"Self-reactive memory-phenotype CD8 T cells exhibit both MHC-restricted and non-MHC-restricted cytotoxicity: a role for the T-cell receptor and natural killer cell receptors","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cytotoxic T cell; NKG2D; Natural killer T cell; Biology; Interleukin 21; IL-2 receptor; CD8; Cell biology; Antigen-presenting cell; ZAP70; T-cell receptor; T cell; Major histocompatibility complex; Interleukin 12; Immunology; Molecular biology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001286368,0.0003877055,0.0003666304,0.0001683832,0.0005570371,0.00007524537,0.0002065554,0.0004161157,0.0003000809],"category_scores_gemma":[0.00006895235,0.0002965348,0.0001323935,0.0002720249,0.0001547649,0.0002376954,0.0001104152,0.0006644475,0.0002217469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007876918,"about_ca_system_score_gemma":0.0001101477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003041955,"about_ca_topic_score_gemma":0.00002286307,"domain_scores_codex":[0.9983469,0.0001359685,0.0003896411,0.0005531462,0.00007083711,0.0005034842],"domain_scores_gemma":[0.9987563,0.000429571,0.0002751052,0.0003432503,0.0001369545,0.00005876047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005749515,0.0008146341,0.00007190404,0.00003945196,0.0003261639,0.000001492381,0.001252642,0.000007977224,0.9901777,0.00002258829,0.006387484,0.0003229941],"study_design_scores_gemma":[0.008543942,0.0007851251,0.0009424184,0.00003220993,0.0004063411,0.00003141012,0.001347951,0.00002728738,0.9319696,0.00002694167,0.05549154,0.0003952369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864843,0.005134708,0.0001359922,0.0002827011,0.004576429,0.001398046,0.00001894667,0.0001880564,0.001780845],"genre_scores_gemma":[0.9879389,0.0007120362,0.0004154215,0.000331165,0.0001396949,0.0001169166,0.0001576366,0.00005589785,0.01013234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05820812,"threshold_uncertainty_score":0.9999487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004344197012567905,"score_gpt":0.191535186645749,"score_spread":0.187190989633181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}