{"id":"W2060944287","doi":"10.1182/blood-2004-01-0150","title":"Self-reactive memory-phenotype CD8 T cells exhibit both MHC-restricted and non-MHC-restricted cytotoxicity: a role for the T-cell receptor and natural killer cell receptors","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cytotoxic T cell; NKG2D; Natural killer T cell; Biology; Interleukin 21; IL-2 receptor; CD8; Cell biology; Antigen-presenting cell; ZAP70; T-cell receptor; T cell; Major histocompatibility complex; Interleukin 12; Immunology; Molecular biology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001113209,0.0003327641,0.0001712762,0.0002043116,0.00007827597,0.0002954009,0.0002009747,0.0003164399,0.0013349],"category_scores_gemma":[0.00009977654,0.0001156548,0.0001379398,0.00009021129,0.0001464813,0.0002553699,0.0002242615,0.0003825524,0.0005336765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001041482,"about_ca_system_score_gemma":0.00007763214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005846746,"about_ca_topic_score_gemma":0.0001077711,"domain_scores_codex":[0.9998749,0.00001241062,0.00001692139,0.000031201,0.00002532618,0.00003926103],"domain_scores_gemma":[0.9998654,0.0000142771,0.00004293933,0.00002862341,0.00002098259,0.00002773651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005247516,0.00001853534,0.0008420511,0.00002524455,0.000004073278,0.00008064725,0.00001692362,0.00003123288,0.9956822,0.0001245507,0.00002516264,0.00309683],"study_design_scores_gemma":[0.00004736674,0.0005115184,0.01140947,0.00001288846,0.00002854389,0.002807685,0.00004225628,0.0009804275,0.9806769,0.0003008375,0.003173745,0.000008383433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99389,0.00111068,0.003519095,0.0000526838,0.00001018791,0.00001361774,0.00007605679,0.0001799731,0.001147636],"genre_scores_gemma":[0.9959393,0.0003091332,0.001646179,0.00003449668,0.00001183311,0.00002037594,0.0001745276,0.00001750385,0.001846813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013349,"threshold_uncertainty_score":0.004465699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004344197012567905,"score_gpt":0.191535186645749,"score_spread":0.187190989633181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}