{"id":"W2060988637","doi":"10.1371/journal.ppat.1004517","title":"GITR Intrinsically Sustains Early Type 1 and Late Follicular Helper CD4 T Cell Accumulation to Control a Chronic Viral Infection","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Sanofi Pasteur; National Institutes of Health; University of Toronto; Sanofi","keywords":"Biology; T cell; CD8; Cytotoxic T cell; Lymphocytic choriomeningitis; Interleukin 21; Priming (agriculture); Immunology; Immune system; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001173978,0.0003662373,0.0002434886,0.0002424426,0.0001030948,0.0003149867,0.0002733983,0.0002906224,0.001004023],"category_scores_gemma":[0.000112259,0.0001507668,0.0002246152,0.00008432653,0.0002979377,0.000176076,0.0003284414,0.001131548,0.0004834397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002552735,"about_ca_system_score_gemma":0.0002177467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003383866,"about_ca_topic_score_gemma":0.0006536826,"domain_scores_codex":[0.9998127,0.00001856005,0.00001123721,0.00003701484,0.00003191505,0.00008869589],"domain_scores_gemma":[0.999787,0.00001724079,0.00005861239,0.00003377379,0.00001475504,0.00008855567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000767895,0.00001618394,0.0001164127,0.00001362564,0.000001704082,0.00003544899,0.000008527676,0.00002102133,0.9991325,0.00004644057,0.0000195331,0.0005119069],"study_design_scores_gemma":[0.00004755455,0.0009897415,0.008892366,0.00001563252,0.00002654881,0.000730473,0.00006597071,0.0007684781,0.9843024,0.0001519241,0.004001086,0.000007858157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960095,0.00102485,0.001376464,0.00008824422,0.00002970047,0.00001797203,0.000223604,0.0002165711,0.001013143],"genre_scores_gemma":[0.9954197,0.0004565213,0.00130458,0.00006197557,0.00002184,0.00002725005,0.00035172,0.0000456622,0.002310783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001004023,"threshold_uncertainty_score":0.003358722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02210137581043729,"score_gpt":0.2456507726506847,"score_spread":0.2235493968402474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}