{"id":"W2061029035","doi":"10.1002/art.27608","title":"Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model","year":2010,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Rush University; U.S. Department of Veterans Affairs","keywords":"Osteoarthritis; Medicine; Nociception; Spinal cord; Hyperalgesia; Knee Joint; Dorsal root ganglion; Joint pain; Sensory system; Neuropathic pain; Nociceptor; Cartilage; Medial meniscus; Knee pain; Meniscus; Chronic pain; Pathology; Anatomy; Anesthesia; Neuroscience; Internal medicine; Surgery; Psychology; Physical therapy; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005681152,0.0001582133,0.0002657757,0.00011864,0.0001156874,0.00002880052,0.00004485164,0.00007801393,0.0000875581],"category_scores_gemma":[0.0001537959,0.0001653628,0.00004415478,0.00006289643,0.00006842631,0.0001903613,0.00003438161,0.0001344894,0.00001425014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001468975,"about_ca_system_score_gemma":0.00005182708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008170131,"about_ca_topic_score_gemma":0.0001426133,"domain_scores_codex":[0.9988026,0.000181872,0.0002828505,0.0002969466,0.0002219902,0.0002137497],"domain_scores_gemma":[0.9992439,0.00005872154,0.00006010237,0.0003112952,0.00005265297,0.000273295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005833429,0.0002164305,0.00044282,0.000009612519,0.000009794509,0.00007645527,0.00109655,0.00001242164,0.8055075,0.001227115,0.00006375107,0.1907542],"study_design_scores_gemma":[0.02985601,0.0443185,0.07991003,0.003687051,0.00009337384,0.003413681,0.002111292,0.06506879,0.7641892,0.004664111,0.001221646,0.001466309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958328,0.0005972548,0.002248542,0.0005643486,0.0001157626,0.0004541539,0.00003819335,0.00005073414,0.00009822242],"genre_scores_gemma":[0.9771859,0.0001143886,0.02192867,0.0005395558,0.00002045487,0.00006078979,0.00002112312,0.00002748552,0.0001016354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1892879,"threshold_uncertainty_score":0.6743298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01555101374192363,"score_gpt":0.2829158241996899,"score_spread":0.2673648104577662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}