{"id":"W2061038239","doi":"10.1371/journal.pone.0077346","title":"Antigen Presenting B Cells Facilitate CD4 T Cell Cooperation Resulting in Enhanced Generation of Effector and Memory CD4 T Cells","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Epitope; Antigen-presenting cell; T cell; Cell biology; Biology; Antigen; Streptamer; Antigen presentation; Effector; Interleukin 21; Autoimmunity; Immunology; Molecular biology; Antibody; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000304676,0.0005212821,0.0002639692,0.000242083,0.0001442355,0.0003440913,0.0001844659,0.000292035,0.001786137],"category_scores_gemma":[0.0001494705,0.0001512593,0.0002230886,0.0001040063,0.000151186,0.0002238125,0.0004043647,0.0006374166,0.0007311364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001218237,"about_ca_system_score_gemma":0.0001403014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001107309,"about_ca_topic_score_gemma":0.000136499,"domain_scores_codex":[0.9997476,0.00007144832,0.00001204615,0.00004212039,0.00004790956,0.00007892265],"domain_scores_gemma":[0.999837,0.00004557975,0.00002877356,0.00002406575,0.00001167001,0.00005282787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000136435,0.00005441103,0.0001567314,0.00002445094,0.000003401338,0.00004678565,0.00001472228,0.00009571033,0.997877,0.0001162878,0.00002895547,0.001444993],"study_design_scores_gemma":[0.00009030441,0.001028391,0.003082952,0.000008967084,0.00002295924,0.000400379,0.00002373075,0.00154456,0.9906184,0.0002768186,0.002897682,0.000004958044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921601,0.001057753,0.003933725,0.00007914082,0.00002009647,0.00002035228,0.00005151756,0.0001080117,0.002569192],"genre_scores_gemma":[0.9942535,0.0003545012,0.003403675,0.00004007328,0.00002248355,0.00002867108,0.00009459432,0.0000163109,0.001786191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001786137,"threshold_uncertainty_score":0.005975246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03427931834292639,"score_gpt":0.2130389814782008,"score_spread":0.1787596631352744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}