{"id":"W2061112849","doi":"10.1371/journal.pone.0017248","title":"Drosophila S2 Cells Are Non-Permissive for Vaccinia Virus DNA Replication Following Entry via Low pH-Dependent Endocytosis and Early Transcription","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"NHLBI Division of Intramural Research; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; National Institute of Allergy and Infectious Diseases; Medical College of Wisconsin; National Institutes of Health; University of Alberta","keywords":"Biology; Transfection; Molecular biology; Viral replication; Schneider 2 cells; Gene; Cell biology; Virus; RNA interference; Virology; RNA; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002255592,0.0001975251,0.0003483779,0.0001181913,0.0002418917,0.00002503663,0.00021066,0.0002528729,0.0001751194],"category_scores_gemma":[0.00007923463,0.0001925607,0.0001341615,0.00007575097,0.00005455756,0.0002027822,0.00004739434,0.0002556167,0.0002244879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005133278,"about_ca_system_score_gemma":0.00003397011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002113786,"about_ca_topic_score_gemma":0.00002835902,"domain_scores_codex":[0.9985364,0.00009668207,0.000291304,0.0005158588,0.00008457439,0.0004751561],"domain_scores_gemma":[0.9991854,0.00008694743,0.0001308692,0.000431826,0.00009284727,0.00007206215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007217589,0.0007998384,0.001797942,0.00009262282,0.0005119188,0.000008725255,0.001056371,4.126095e-8,0.9927765,0.00002102449,0.0001714703,0.002041752],"study_design_scores_gemma":[0.002144365,0.0004282704,0.01499626,0.0001203238,0.0002024654,0.000006137565,0.00007320997,0.00001181906,0.9812903,0.000343862,0.0001786164,0.0002043383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967579,0.001158241,0.0002812968,0.0001194279,0.0001334217,0.0009452924,0.0001441408,0.00007041731,0.0003898363],"genre_scores_gemma":[0.997686,0.0003791402,0.0002153187,0.0001066704,0.00005981168,0.0002586722,0.00007201405,0.00003119649,0.001191186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01319832,"threshold_uncertainty_score":0.7852396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04087646705162691,"score_gpt":0.2398125215137393,"score_spread":0.1989360544621124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}