{"id":"W2061120468","doi":"10.1038/sj.cdd.4402116","title":"A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance","year":2007,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Université Laval","funders":"National Health and Medical Research Council; Australian Research Council; Medical Research Council; Pfizer","keywords":"Oxidative stress; DNA damage; Poly ADP ribose polymerase; Apoptosis; Reactive oxygen species; Programmed cell death; DNA repair; Biology; Cell biology; Cytochrome c; Polymerase; Chemistry; Molecular biology; Genetics; DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009371922,0.0001168532,0.0001249984,0.00003093672,0.00004526128,0.00001718676,0.00005227171,0.0001070016,0.00000564448],"category_scores_gemma":[0.00001591925,0.0001100039,0.00003172063,0.00003253854,0.00002710378,0.000008651563,0.00005077656,0.00003548002,3.355083e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007160916,"about_ca_system_score_gemma":0.000008713984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007547781,"about_ca_topic_score_gemma":0.00001413264,"domain_scores_codex":[0.9993383,0.00001314726,0.0001730158,0.0002390674,0.00008860965,0.0001478798],"domain_scores_gemma":[0.9995869,0.00001184794,0.0001408482,0.0001350451,0.00005183196,0.00007354363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001619229,0.00008132119,0.002712351,0.00009947018,0.00001891681,1.037741e-7,0.00006011581,1.460982e-8,0.9959313,0.0001435731,0.0000226088,0.0007683443],"study_design_scores_gemma":[0.0008328144,0.0001105207,0.01970381,0.00001808487,0.00002623023,5.171674e-7,0.00003955006,0.00001856793,0.9782767,0.00008243295,0.0007744023,0.0001163746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9402425,0.0004516715,0.05867741,0.000006096723,0.0000406441,0.0002073817,0.0001160889,0.000007443297,0.000250799],"genre_scores_gemma":[0.9963287,0.0001908843,0.002201161,0.00002729493,0.00003640135,0.00001383181,0.0004202105,0.00001148259,0.0007700832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05647625,"threshold_uncertainty_score":0.4485828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007067163911162651,"score_gpt":0.2141493072584998,"score_spread":0.2070821433473371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}