{"id":"W2061130471","doi":"10.1021/np401019t","title":"Discovery, Isolation, and Structure Elucidation of Dretamycin","year":2014,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Candida albicans; Mutant; Heterozygote advantage; Compound heterozygosity; Biology; Streptomyces; Phenotypic screening; Isolation (microbiology); Phenotype; Genetics; Gene; Microbiology; Allele; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009642304,0.0002962197,0.00016348,0.0003497579,0.0001357195,0.0002050464,0.0002190643,0.0002231388,0.0008175066],"category_scores_gemma":[0.000210394,0.00008973725,0.000151802,0.0003021455,0.0001211347,0.000213543,0.0001970756,0.0005853949,0.000481313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001638783,"about_ca_system_score_gemma":0.0004007694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00044556,"about_ca_topic_score_gemma":0.0009200852,"domain_scores_codex":[0.999958,0.000005972123,0.000003940892,0.00001013347,0.00001352341,0.000008502835],"domain_scores_gemma":[0.9999336,0.000009923387,0.00001489089,0.000009050404,0.00001535687,0.00001710433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005034322,0.00004078139,0.0002763084,0.00006169127,0.000005914751,0.0003252184,0.00002689479,0.0002792274,0.984734,0.0003768148,0.0001483465,0.01367445],"study_design_scores_gemma":[0.00002135977,0.000313767,0.002330816,0.00001467498,0.00001395698,0.0008127359,0.00003563944,0.0004422354,0.9799238,0.0001502372,0.01593089,0.00001000245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9420536,0.00921949,0.03368393,0.0007621509,0.00009731566,0.0003288924,0.003719959,0.0002416003,0.009892998],"genre_scores_gemma":[0.9395433,0.006890736,0.04158196,0.0003081895,0.00003890669,0.00006963604,0.004104809,0.0000442108,0.007418334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008175066,"threshold_uncertainty_score":0.00273484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005892046867466415,"score_gpt":0.2246346616004748,"score_spread":0.2187426147330084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}