{"id":"W2061155447","doi":"10.1021/bi4009374","title":"The Hydrophobic Region of the DmsA Twin-Arginine Leader Peptide Determines Specificity with Chaperone DmsD","year":2013,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chaperone (clinical); Arginine; Peptide; Chemistry; Biophysics; Biochemistry; Cell biology; Amino acid; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001084852,0.0002059372,0.0001483805,0.000008723112,0.0001807734,0.0000332233,0.000500461,0.0001629617,0.00004107595],"category_scores_gemma":[0.00006471636,0.00011064,0.0001129085,0.00008664974,0.0003200044,0.000004177894,0.0001326414,0.00009738732,0.00001381671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001153785,"about_ca_system_score_gemma":0.00005487717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002654369,"about_ca_topic_score_gemma":0.000006574457,"domain_scores_codex":[0.9989362,0.00004539365,0.0002227073,0.0003298528,0.0001951449,0.0002706799],"domain_scores_gemma":[0.9987575,0.00002684002,0.0001823888,0.0008616645,0.0001065353,0.00006503261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000672196,0.00002900554,0.0004750809,0.00002583334,0.00003045731,0.000001509879,0.00002279259,0.000002375776,0.9960471,0.000008513784,0.002102465,0.001187582],"study_design_scores_gemma":[0.0002289058,0.0001124508,0.000781757,0.00004437002,0.00001585374,0.00006073156,0.0001594885,0.00001495477,0.9912602,0.00006640272,0.007084674,0.0001702647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961408,0.0009163232,0.0001354096,0.0007283135,0.00009671255,0.0002794751,0.000004799586,0.00001098036,0.001687192],"genre_scores_gemma":[0.9895915,0.0001374469,0.0002291209,0.0001198589,0.0003119408,0.00006963917,0.000009599215,0.00002715196,0.009503721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00781653,"threshold_uncertainty_score":0.4511769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009423716871205585,"score_gpt":0.1969391269091719,"score_spread":0.1875154100379663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}