{"id":"W2061209353","doi":"10.1071/ch14543","title":"Synthesis of Highly Water-Soluble Adamantyl Phosphoinositide Derivatives*","year":2014,"lang":"en","type":"article","venue":"Australian Journal of Chemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Medical Research Council; Medical Research Council; Ministero dello Sviluppo Economico; Ontario Ministry of Economic Development and Innovation; University of Melbourne; Genome Canada; Australian Research Council; Wellcome Trust; GlaxoSmithKline; National Health and Medical Research Council; Pfizer; Eli Lilly and Company","keywords":"Chemistry; Phosphatidylinositol; Side chain; Micelle; Biochemistry; Biocatalysis; Macromolecule; Affinities; Stereochemistry; Chemical biology; Signal transduction; Organic chemistry; Catalysis; Reaction mechanism; Aqueous solution","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003517037,0.0001447484,0.0002483183,0.0000261699,0.00003948736,0.00001722658,0.0002347196,0.0001360407,0.0001600127],"category_scores_gemma":[0.0001486526,0.0001169156,0.0001810355,0.00004938206,0.0001012353,0.000009725863,0.00004140627,0.0001165451,0.000003080087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001252331,"about_ca_system_score_gemma":0.00005501445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003967885,"about_ca_topic_score_gemma":2.584002e-7,"domain_scores_codex":[0.998948,0.00004552974,0.0004608624,0.0001445453,0.0001936055,0.0002074808],"domain_scores_gemma":[0.9990706,0.00001874834,0.0003323603,0.0002217779,0.0002235891,0.0001328614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008941496,0.00004137966,0.0004080165,0.00008692338,0.00007111457,0.000006914735,0.00002177732,0.0001530409,0.9971985,0.00001013836,0.001030047,0.0008827028],"study_design_scores_gemma":[0.0004104734,0.0000940496,0.0002429098,0.0001294182,0.00003897069,0.0001017061,0.00005658118,0.000004273295,0.9893233,0.00009059061,0.009366441,0.0001413033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972526,0.0001372363,0.001026878,0.0003521855,0.00006425416,0.00003822627,0.000005525553,0.000004009647,0.001119023],"genre_scores_gemma":[0.9971899,0.00002521825,0.001415169,0.00004016024,0.0002680402,0.000002190295,0.00001382653,0.00001649981,0.001028993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008336394,"threshold_uncertainty_score":0.4767682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009213219829594924,"score_gpt":0.2294497162956687,"score_spread":0.2202364964660738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}