{"id":"W2061209353","doi":"10.1071/ch14543","title":"Synthesis of Highly Water-Soluble Adamantyl Phosphoinositide Derivatives*","year":2014,"lang":"en","type":"article","venue":"Australian Journal of Chemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Medical Research Council; Medical Research Council; Ministero dello Sviluppo Economico; Ontario Ministry of Economic Development and Innovation; University of Melbourne; Genome Canada; Australian Research Council; Wellcome Trust; GlaxoSmithKline; National Health and Medical Research Council; Pfizer; Eli Lilly and Company","keywords":"Chemistry; Phosphatidylinositol; Side chain; Micelle; Biochemistry; Biocatalysis; Macromolecule; Affinities; Stereochemistry; Chemical biology; Signal transduction; Organic chemistry; Catalysis; Reaction mechanism; Aqueous solution","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001904422,0.0004027205,0.0003517703,0.0001492264,0.0001522576,0.0002843601,0.0003211006,0.0002669893,0.001797927],"category_scores_gemma":[0.000195281,0.0001883431,0.000253486,0.0002369073,0.0001690283,0.0004078085,0.0002379543,0.0007178183,0.0009415846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002233644,"about_ca_system_score_gemma":0.0002176533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000214613,"about_ca_topic_score_gemma":0.0002847022,"domain_scores_codex":[0.9998959,0.00001592341,0.00001458061,0.00002064374,0.0000288577,0.00002410516],"domain_scores_gemma":[0.9998763,0.00002232323,0.00003028415,0.00001866243,0.00002135264,0.00003116366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009878586,0.00003769279,0.00005194243,0.00009849434,0.0000103405,0.0002804174,0.00005364685,0.0004683731,0.9922445,0.0008359727,0.0001667245,0.005653171],"study_design_scores_gemma":[0.00002292786,0.0002398011,0.0002162473,0.00000504564,0.00001539768,0.0002451761,0.00001187822,0.0005345694,0.9881962,0.0001207966,0.01038005,0.00001183995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.934177,0.006548273,0.04409724,0.0004780128,0.0002881191,0.000303778,0.00133735,0.0003844351,0.01238575],"genre_scores_gemma":[0.9578895,0.005381516,0.02458785,0.00007664759,0.00004657649,0.0001159903,0.001295264,0.0001326665,0.01047406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001797927,"threshold_uncertainty_score":0.006014645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009213219829594924,"score_gpt":0.2294497162956687,"score_spread":0.2202364964660738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}