{"id":"W2061259593","doi":"10.1042/bst0360072","title":"AAA+ proteins: diversity in function, similarity in structure","year":2008,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"","keywords":"SUPERFAMILY; AAA proteins; Computational biology; Context (archaeology); Biology; Structural similarity; Function (biology); Evolutionary biology; Lineage (genetic); Functional diversity; Structural Classification of Proteins database; Genetics; Protein structure; ATPase; Biochemistry; Enzyme; Gene; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004600651,0.0006880655,0.001263713,0.00136828,0.0002465617,0.001016703,0.0007658351,0.0007139559,0.002156147],"category_scores_gemma":[0.000440763,0.0002205107,0.0002564095,0.002259807,0.0004461237,0.001287237,0.0005407832,0.001053567,0.003650927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005386231,"about_ca_system_score_gemma":0.0006798198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005085769,"about_ca_topic_score_gemma":0.0005719095,"domain_scores_codex":[0.999826,0.00002113939,0.00002469706,0.00004078884,0.00007232391,0.00001507373],"domain_scores_gemma":[0.9998229,0.00005389381,0.00003439461,0.000007919162,0.00005619092,0.00002473111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005812358,0.0000203969,0.0002298797,0.005079889,0.00004700281,0.0001981022,0.00004915697,0.0001704544,0.003757376,0.003070844,0.01869342,0.9686254],"study_design_scores_gemma":[0.000008149419,0.00004784767,0.0009687399,0.0007764956,0.00004689645,0.001888919,0.0000567321,0.00005753226,0.0009295453,0.001619593,0.9935861,0.00001343237],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004221379,0.9961693,0.0006659796,0.000297205,0.0002484102,0.000005561035,0.00003986944,0.00002985969,0.002121723],"genre_scores_gemma":[0.001913781,0.9956154,0.0007366496,0.0002016306,0.0001652272,0.0000080502,0.00008655385,0.000002865238,0.001269808],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002156147,"threshold_uncertainty_score":0.007212996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02454845556368604,"score_gpt":0.251711173962101,"score_spread":0.2271627183984149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}