{"id":"W2061270368","doi":"10.1074/jbc.m112310200","title":"HIP1 and HIP12 Display Differential Binding to F-actin, AP2, and Clathrin","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Clathrin; Actin; Differential (mechanical device); Cell biology; Actin-binding protein; Chemistry; Biophysics; Biology; Endocytosis; Actin cytoskeleton; Physics; Biochemistry; Receptor; Cytoskeleton; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005801891,0.0001373404,0.0002033196,0.00002465395,0.00008682514,0.00005919203,0.0001483364,0.00007409713,0.0002940306],"category_scores_gemma":[0.0009185747,0.0000918668,0.00005659889,0.00007898585,0.0001314036,0.00004489813,0.0001179942,0.0002082705,0.00000586711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001397336,"about_ca_system_score_gemma":0.000005611465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":2.000493e-7,"about_ca_topic_score_gemma":5.213337e-8,"domain_scores_codex":[0.9990904,0.00005963469,0.0002473615,0.0002537898,0.000156756,0.0001920735],"domain_scores_gemma":[0.9992506,0.0002048718,0.0001424156,0.00008644963,0.00002751624,0.000288138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003903468,0.00007296322,0.005461441,0.00001065336,0.000003081573,0.00004325403,0.00002897873,0.000002029674,0.9927669,0.000007438801,0.0002002378,0.001363946],"study_design_scores_gemma":[0.0003192362,0.0001592201,0.01370867,0.00001913753,0.000009954942,0.0002471813,0.0000273502,0.00004219192,0.9848568,0.00004876703,0.0004455941,0.0001158563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989695,0.0001722638,0.00004738543,0.0004046004,0.00009325761,0.00004729215,0.00001413199,0.000009221423,0.0002423631],"genre_scores_gemma":[0.9990544,0.0002444802,0.0001134007,0.0002345884,0.0001754115,0.00000177056,3.597742e-7,0.000006361966,0.0001692784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008247232,"threshold_uncertainty_score":0.374622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06273105469716664,"score_gpt":0.2729250564416496,"score_spread":0.210194001744483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}