{"id":"W2061307034","doi":"10.1158/0008-5472.can-11-1874","title":"The <i>Pax-5</i> Gene: A Pluripotent Regulator of B-cell Differentiation and Cancer Disease","year":2011,"lang":"en","type":"review","venue":"Cancer Research","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Atlantic Cancer Research Institute; Université de Moncton","funders":"Canadian Institutes of Health Research","keywords":"Biology; Transcription factor; PAX5; Cancer research; Oncogene; B cell; Carcinogenesis; Cancer; Gene; Cell growth; Regulation of gene expression; Lymphopoiesis; Genetics; Cell cycle; Haematopoiesis; Stem cell; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002422952,0.0004779846,0.0006894377,0.001431727,0.0002021882,0.0004849369,0.0004425303,0.0005683175,0.00228379],"category_scores_gemma":[0.0002415974,0.0001284436,0.0002304922,0.001604127,0.000309672,0.0006973977,0.0003635937,0.0007920027,0.00174933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004207627,"about_ca_system_score_gemma":0.0005632634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005780562,"about_ca_topic_score_gemma":0.00114647,"domain_scores_codex":[0.9999179,0.00001133576,0.0000104401,0.00001405099,0.00003747497,0.000008845284],"domain_scores_gemma":[0.9999043,0.00003535091,0.00001609883,0.000003377158,0.00002725131,0.00001358035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005655114,0.00003689851,0.0002663113,0.006562328,0.00004461225,0.0003118037,0.00004859945,0.0002305242,0.005850074,0.003275707,0.02073605,0.9625805],"study_design_scores_gemma":[0.00001049456,0.00005190309,0.001168281,0.001021016,0.00004813779,0.002400459,0.00004333656,0.00005024459,0.001188652,0.001212732,0.992794,0.00001079119],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003171386,0.9968168,0.0002220234,0.0002840593,0.0002194234,0.000004806494,0.00002397096,0.000009587036,0.002102312],"genre_scores_gemma":[0.001001052,0.997142,0.00024741,0.0001607571,0.0001353223,0.000005230896,0.00004231056,0.000001384332,0.001264454],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00228379,"threshold_uncertainty_score":0.007640004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09306024624241326,"score_gpt":0.4063794572088625,"score_spread":0.3133192109664492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}