{"id":"W2061313415","doi":"10.1038/mt.2008.130","title":"A let-7 MicroRNA-sensitive Vesicular Stomatitis Virus Demonstrates Tumor-specific Replication","year":2008,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Discovery Centre; University of Ottawa","funders":"National Cancer Institute","keywords":"Oncolytic virus; Vesicular stomatitis virus; Biology; microRNA; Viral replication; Virus; Cancer cell; Vesicular Stomatitis; Virology; Gene; Cancer; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000244573,0.0002154653,0.0002109709,0.0001795494,0.0001450291,0.0003938351,0.000227431,0.000479385,0.000685379],"category_scores_gemma":[0.000252423,0.0001685185,0.0002344329,0.00008573167,0.0002948112,0.0002345953,0.000217661,0.0005223391,0.0005447306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002517898,"about_ca_system_score_gemma":0.0002973305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002420048,"about_ca_topic_score_gemma":0.0003907493,"domain_scores_codex":[0.9998335,0.00003121429,0.00001685705,0.00003242073,0.00006297293,0.00002314479],"domain_scores_gemma":[0.9998709,0.00003376246,0.00002851534,0.00002090058,0.00002084217,0.00002512327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001800584,0.000007037852,0.00003965781,0.00001100548,0.000001701478,0.0000205633,0.000005828862,0.00003148845,0.9984609,0.0004860383,0.00003449883,0.0008833745],"study_design_scores_gemma":[0.000005326548,0.0001161953,0.0002310868,0.000001815642,0.000004544018,0.0002327021,0.000003546798,0.0004957962,0.9956359,0.00008848614,0.003181433,0.000003104803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9397866,0.002183671,0.04833844,0.0004321636,0.0002077861,0.0001071547,0.0002698972,0.0005243617,0.008149937],"genre_scores_gemma":[0.9707483,0.000673888,0.02383414,0.00009520539,0.00001686542,0.00004573697,0.0003154398,0.00007296713,0.004197355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000685379,"threshold_uncertainty_score":0.002292871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02106723143707975,"score_gpt":0.2718457248246023,"score_spread":0.2507784933875226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}