{"id":"W2061335198","doi":"10.1111/j.1474-9726.2007.00347.x","title":"Mitochondrial function and apoptotic susceptibility in aging skeletal muscle","year":2007,"lang":"en","type":"article","venue":"Aging Cell","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":432,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Biology; Mitochondrial biogenesis; Skeletal muscle; Mitochondrion; Internal medicine; Sarcopenia; Endocrinology; Reactive oxygen species; Mitochondrial DNA; Apoptosis; Coactivator; Myocyte; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003189204,0.0001219678,0.0001093647,0.0000725963,0.00006151076,0.00001714841,0.00006206633,0.0001386623,0.00004908686],"category_scores_gemma":[0.00004955439,0.0001278074,0.00004863553,0.00009270175,0.00005810285,0.000005366148,0.00006091802,0.0001378486,0.00001876668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001515233,"about_ca_system_score_gemma":0.00002144941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006341806,"about_ca_topic_score_gemma":0.000427747,"domain_scores_codex":[0.998992,0.00006319694,0.0002006807,0.0003967427,0.00007461035,0.000272727],"domain_scores_gemma":[0.9996011,0.00002577944,0.00004808857,0.0002221213,0.00002748726,0.00007543113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005544707,0.00004906763,0.01371838,0.00002043569,0.000004143601,0.000005909348,0.00008414643,0.00002446925,0.9822533,0.00002587185,0.0003611266,0.003397763],"study_design_scores_gemma":[0.00696065,0.001211819,0.34562,0.00004963494,0.00007765617,0.00006646644,0.001097469,0.0002246477,0.4989345,0.0008131402,0.1437798,0.001164132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817278,0.0003272094,0.01433697,0.00006194938,0.001217718,0.0001440881,0.00000168401,0.00001926933,0.002163281],"genre_scores_gemma":[0.997316,0.00002853835,0.0008332325,0.0002833647,0.000663508,0.000003365437,0.00004393324,0.00001454328,0.0008135176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4833187,"threshold_uncertainty_score":0.5211836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00797374194668022,"score_gpt":0.2366777428566115,"score_spread":0.2287040009099313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}