{"id":"W2061353017","doi":"10.1002/gepi.20125","title":"Validity, efficiency, and robustness of a family‐based test of association","year":2005,"lang":"en","type":"article","venue":"Genetic Epidemiology","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Population stratification; Statistics; Robustness (evolution); Score test; Test statistic; Statistic; Association test; Type I and type II errors; Genetic association; Population; Mathematics; Statistical power; Allele; Statistical hypothesis testing; Econometrics; Genetics; Biology; Genotype; Demography; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"simulation_or_modeling","genre":"methods","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"methods","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00225602,0.0001733647,0.0005978391,0.00008261167,0.0000518511,0.000001577063,0.000195168,0.0004286742,0.00001841642],"category_scores_gemma":[0.006406222,0.0001669447,0.0001333411,0.0001216626,0.000193369,0.000001866898,0.0001113333,0.00009875236,0.000003351686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003211472,"about_ca_system_score_gemma":0.0001146547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005121236,"about_ca_topic_score_gemma":0.00004928974,"domain_scores_codex":[0.997587,0.0006484684,0.0008711604,0.0003981588,0.00009734811,0.0003978469],"domain_scores_gemma":[0.9972533,0.001339029,0.0007520308,0.0003580656,0.0002132014,0.00008437473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00002147682,0.0001478381,0.896859,0.00003651048,0.00004317857,1.506882e-7,0.00001727875,0.04021189,0.05459441,0.00004472365,0.002990066,0.005033396],"study_design_scores_gemma":[0.0009365996,0.0008704875,0.9412913,0.00001711079,0.00008466363,0.00000821073,0.00003951046,0.04223749,0.00933812,0.0003349854,0.004589712,0.0002518402],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9160726,0.001652198,0.08058588,0.001001127,0.0001294444,0.0001717151,0.00004367498,0.000007723916,0.000335645],"genre_scores_gemma":[0.9353671,0.0005229717,0.06323171,0.00042223,0.0002135242,0.00001994262,0.00004611974,0.00001508092,0.0001613318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04525629,"threshold_uncertainty_score":0.7669308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03738183606448306,"score_gpt":0.3033789616436319,"score_spread":0.2659971255791488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}