{"id":"W2061391296","doi":"10.1111/j.1600-0854.2011.01277.x","title":"HIV‐1 Vpu Antagonizes BST‐2 by Interfering Mainly with the Trafficking of Newly Synthesized BST‐2 to the Cell Surface","year":2011,"lang":"en","type":"article","venue":"Traffic","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Endosome; Tetherin; Endocytic cycle; Cell biology; Biology; Jurkat cells; Cell; Intracellular; Endocytosis; HeLa; Cell membrane; Downregulation and upregulation; Transport protein; Virology; T cell; Virus; Biochemistry; Viral envelope; Immunology; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003182909,0.0002158806,0.000274927,0.0000436945,0.0002429087,0.00001970193,0.0005296438,0.00008938064,0.0004241946],"category_scores_gemma":[0.00001882916,0.0001064009,0.00008836394,0.0001734048,0.0002742863,0.00004763497,0.0000718035,0.0002760085,0.0009045962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000033544,"about_ca_system_score_gemma":0.00006826268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001035548,"about_ca_topic_score_gemma":0.0001630868,"domain_scores_codex":[0.998659,0.0002569101,0.000215704,0.0002805211,0.00007093888,0.0005169298],"domain_scores_gemma":[0.9990808,0.000308434,0.00008253939,0.000435816,0.00004591999,0.00004645788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004867021,0.001582225,0.001324081,0.0001234484,0.001378443,0.00007381324,0.04361187,0.002094482,0.8568528,0.0001727914,0.05287052,0.03504847],"study_design_scores_gemma":[0.00465003,0.001963496,0.002921568,0.0001618845,0.0002150073,0.00009920987,0.008136232,0.00006278015,0.9365894,0.000003289389,0.04469558,0.0005015588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947825,0.001724092,0.0003126016,0.0009335134,0.00009219184,0.0005231044,0.00007878018,0.00007555717,0.001477677],"genre_scores_gemma":[0.9973353,0.00007350943,0.0002700825,0.00007649854,0.00001127929,0.00003149429,0.00002763387,0.00002734178,0.002146935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07973653,"threshold_uncertainty_score":0.9998733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01550089721869101,"score_gpt":0.213961364890115,"score_spread":0.198460467671424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}