{"id":"W2061391296","doi":"10.1111/j.1600-0854.2011.01277.x","title":"HIV‐1 Vpu Antagonizes BST‐2 by Interfering Mainly with the Trafficking of Newly Synthesized BST‐2 to the Cell Surface","year":2011,"lang":"en","type":"article","venue":"Traffic","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Endosome; Tetherin; Endocytic cycle; Cell biology; Biology; Jurkat cells; Cell; Intracellular; Endocytosis; HeLa; Cell membrane; Downregulation and upregulation; Transport protein; Virology; T cell; Virus; Biochemistry; Viral envelope; Immunology; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001414215,0.0004575396,0.0002521692,0.0001476509,0.0001060718,0.0003455056,0.0002406587,0.000235363,0.0005508079],"category_scores_gemma":[0.0001308248,0.0001138796,0.0002133458,0.00009934892,0.0002564682,0.0001720143,0.0001641058,0.000388072,0.0001776611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002364708,"about_ca_system_score_gemma":0.0001344278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003690418,"about_ca_topic_score_gemma":0.0003362496,"domain_scores_codex":[0.9998637,0.00003973149,0.00001239328,0.00002608822,0.00002647006,0.00003155294],"domain_scores_gemma":[0.9999468,0.00001959845,0.00001162294,0.000008425073,0.000004834133,0.000008562068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006922241,0.00001892199,0.00005245077,0.00001534304,0.000002505799,0.00002082614,0.000005525983,0.00005604588,0.9991013,0.00006884406,0.000007456503,0.0005817296],"study_design_scores_gemma":[0.000005963402,0.0002576782,0.0006997653,0.000001375186,0.000004465581,0.00007701523,0.000004381669,0.0004701763,0.9980105,0.0000136419,0.0004539201,0.000001193909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968864,0.0008324976,0.001517014,0.00002255789,0.00001220257,0.00001733571,0.00007586283,0.00003464755,0.000601339],"genre_scores_gemma":[0.9966435,0.0006348849,0.001523713,0.00001884596,0.00001046601,0.00002822487,0.0001877051,0.00001583595,0.0009368184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005508079,"threshold_uncertainty_score":0.001842618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01550089721869101,"score_gpt":0.213961364890115,"score_spread":0.198460467671424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}