{"id":"W2061399161","doi":"10.1016/j.ygyno.2005.12.020","title":"A phase III randomized trial of BAY 12-9566 (tanomastat) as maintenance therapy in patients with advanced ovarian cancer responsive to primary surgery and paclitaxel/platinum containing chemotherapy: A National Cancer Institute of Canada Clinical Trials Group Study","year":2006,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; Bayer (Canada); University of Manitoba; Nova Scotia Cancer Centre; Health Sciences Centre; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Clinical endpoint; Chemotherapy; Ovarian cancer; Interim analysis; Carboplatin; Oncology; Surgery; Placebo; Gemcitabine; Cancer; Paclitaxel; Randomized controlled trial; Pathology; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005013832,0.0002406232,0.00173403,0.0001102772,0.00005655667,0.000006013963,0.0001291316,0.0002295502,0.00005161594],"category_scores_gemma":[0.002957032,0.0001778595,0.0001376096,0.0001499188,0.0001951051,0.00001506839,0.00006255534,0.0001478641,9.270765e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002666435,"about_ca_system_score_gemma":0.003440417,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01831317,"about_ca_topic_score_gemma":0.1423877,"domain_scores_codex":[0.9957335,0.001668139,0.001483756,0.0005080655,0.0002784884,0.0003280696],"domain_scores_gemma":[0.9968399,0.001461427,0.001071409,0.000184306,0.0003501381,0.00009285365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9544449,0.002858435,0.009399827,0.00001094006,0.0003342568,0.00002273755,0.0001078817,0.00005915692,0.0129831,0.00009671634,0.0006550062,0.01902708],"study_design_scores_gemma":[0.9489583,0.02267719,0.01897881,0.00004916053,0.00005608296,0.00000140331,0.0001499645,0.000009905823,0.004404079,0.0002814534,0.004153153,0.0002805336],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934667,0.0002369552,0.0001178239,0.0002905041,0.0008068696,0.004672496,0.0001307522,0.000005479601,0.000272429],"genre_scores_gemma":[0.9963995,0.0002117397,0.0005356108,0.001186027,0.0001938829,0.001299875,0.00008466865,0.00001725532,0.00007144535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1240745,"threshold_uncertainty_score":0.988224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02761768728875214,"score_gpt":0.3488508885259267,"score_spread":0.3212332012371746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}