{"id":"W2061407675","doi":"10.1074/jbc.m206978200","title":"Structure of Arterivirus nsp4","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"Basic Energy Sciences; National Center for Research Resources; Canadian Institutes of Health Research; Office of Science; Alberta Heritage Foundation for Medical Research; National Institutes of Health; University of Alberta; Fondation pour la Recherche Médicale; U.S. Department of Energy","keywords":"Arterivirus; Biology; Oxyanion hole; Polyproteins; RNA; Catalytic triad; RNA-dependent RNA polymerase; Gene; Virology; Chymotrypsin; Recombinant DNA; Molecular biology; Genetics; Biochemistry; Peptide sequence; Enzyme; Trypsin; Active site","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007079916,0.0002399567,0.000157533,0.0001855289,0.0003494762,0.0002767707,0.0002771856,0.0002120931,0.001762607],"category_scores_gemma":[0.0002085969,0.0001388219,0.0001571924,0.000209963,0.0001496642,0.0001808985,0.0001811476,0.0003725347,0.0007436841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005471123,"about_ca_system_score_gemma":0.0004080147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003663879,"about_ca_topic_score_gemma":0.0019562,"domain_scores_codex":[0.9999608,0.000005111925,0.000002396691,0.00001114401,0.0000120661,0.000008507457],"domain_scores_gemma":[0.9999222,0.000008150923,0.00001741383,0.000005226864,0.00002204394,0.00002504491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006672873,0.00006103226,0.004587404,0.0002248787,0.00003509491,0.001295011,0.0002697852,0.00327851,0.9691718,0.003095014,0.00182822,0.01548591],"study_design_scores_gemma":[0.000270153,0.001900646,0.1516891,0.0002146458,0.0002168903,0.006602423,0.0006852223,0.06164748,0.5966665,0.01011774,0.1697534,0.00023596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855071,0.003399185,0.002960234,0.0002200267,0.00004246632,0.00003204315,0.0007177935,0.00006595503,0.007055192],"genre_scores_gemma":[0.9795529,0.001772328,0.003940201,0.0001428967,0.00003731077,0.00002511466,0.006275702,0.00002428437,0.008229211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003663879,"threshold_uncertainty_score":0.007285058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03874798161435553,"score_gpt":0.2213411127737625,"score_spread":0.182593131159407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}