{"id":"W2061478016","doi":"10.1093/nar/gkt212","title":"Zebrafish AID is capable of deaminating methylated deoxycytidines","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Cytidine deaminase; Activation-induced (cytidine) deaminase; Deamination; Biology; Zebrafish; DNA demethylation; Cytidine; APOBEC3G; Genetics; DNA; Biochemistry; Cell biology; Gene; DNA methylation; Antibody; Enzyme; Somatic hypermutation; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009038625,0.0002758666,0.0001493594,0.0001424597,0.0001431779,0.0001592269,0.0001642652,0.0001993024,0.0008709037],"category_scores_gemma":[0.0001004216,0.0001558691,0.0001683979,0.00006677629,0.0002271373,0.00008000434,0.000218494,0.0002695223,0.000316541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00038689,"about_ca_system_score_gemma":0.0002226487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002429167,"about_ca_topic_score_gemma":0.003984958,"domain_scores_codex":[0.9999474,0.000004266549,0.000003425566,0.00001240146,0.00002006711,0.00001239224],"domain_scores_gemma":[0.9999387,0.000008434788,0.00001928759,0.000007832721,0.000009086029,0.00001668816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002013437,0.000001961437,0.0001991197,0.00001795698,0.000001796848,0.00004077701,0.000006462169,0.00009824894,0.9988309,0.00009949906,0.00001772242,0.0006655503],"study_design_scores_gemma":[0.000005750186,0.00006913663,0.00272993,0.000003532145,0.00001177053,0.0001981024,0.00001103072,0.0008584342,0.9926392,0.00006012237,0.003408156,0.000004901715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992846,0.0006725485,0.004190332,0.00006143532,0.00001265043,0.00001038531,0.0002180746,0.0001025922,0.001886069],"genre_scores_gemma":[0.9920123,0.0002995943,0.004281158,0.0000165848,0.000002037296,0.000008834981,0.0002685663,0.00001687819,0.003094075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002429167,"threshold_uncertainty_score":0.004830122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0366812095614173,"score_gpt":0.3356118111455393,"score_spread":0.298930601584122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}