{"id":"W2061515984","doi":"10.1074/jbc.m303371200","title":"Structure and Ligand-induced Conformational Change of the 39-kDa Glycoprotein from Human Articular Chondrocytes","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Studies on Chitinases and Chitosanases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"Directorate for Biological Sciences; European Synchrotron Radiation Facility; Wellcome Trust","keywords":"Glycoprotein; Cell biology; Ligand (biochemistry); Signal transduction; Lectin; Biology; Chemistry; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007433203,0.0001258738,0.0002040286,0.000006898216,0.00008554519,0.00001164202,0.0001533923,0.0001670895,0.00006011545],"category_scores_gemma":[0.0002270538,0.00007145761,0.0001300167,0.00004181184,0.0001262765,0.000004322756,0.00007163457,0.0001463879,1.600189e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006710656,"about_ca_system_score_gemma":0.00002875291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005629597,"about_ca_topic_score_gemma":0.000002898103,"domain_scores_codex":[0.9992776,0.00003241895,0.0003165102,0.0001201161,0.0001299444,0.0001234011],"domain_scores_gemma":[0.9993533,0.0000217068,0.0003339795,0.0001363945,0.00009193941,0.00006267269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003853328,0.00003183572,0.009778455,0.00001511704,0.00006543247,0.000002524811,0.00002423096,9.805318e-7,0.9897887,0.00002457794,0.00007836396,0.0001512135],"study_design_scores_gemma":[0.0005138094,0.0001598871,0.03280414,0.00003357824,0.00002048833,0.00006171986,0.0001910352,7.558636e-7,0.9645676,0.0003020125,0.001253865,0.00009108851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974746,0.002048234,0.000006944696,0.0001030944,0.00006262526,0.00006481908,0.00005262726,0.000001726504,0.0001853752],"genre_scores_gemma":[0.9992194,0.0001442223,0.0001268297,0.0001740927,0.0003008257,0.000002565967,0.000016928,0.000004574516,0.00001060685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02522112,"threshold_uncertainty_score":0.2913957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02347250577413703,"score_gpt":0.2464270599073917,"score_spread":0.2229545541332546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}