{"id":"W2061603911","doi":"10.1128/aac.46.9.3096-3100.2002","title":"Effect of the Echinocandin Caspofungin on Expression of <i>Candida albicans</i> Secretory Aspartyl Proteinases and Phospholipase In Vitro","year":2002,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Caspofungin; Echinocandins; Echinocandin; Candida albicans; Microbiology; Corpus albicans; Biology; Miconazole; In vitro; Phospholipase; Virulence; Fungal protein; Fungicide; Enzyme; Biochemistry; Gene; Antifungal; Amphotericin B; Saccharomyces cerevisiae; Fluconazole","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001587099,0.0003265883,0.0002357264,0.0001256345,0.0001198807,0.0004024611,0.0001388266,0.0002057258,0.0006827888],"category_scores_gemma":[0.0003022221,0.000109698,0.0001518008,0.0001404397,0.0001552211,0.0001729186,0.000139706,0.0004251652,0.0002671141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003137558,"about_ca_system_score_gemma":0.0001886227,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000804379,"about_ca_topic_score_gemma":0.0009272852,"domain_scores_codex":[0.9998016,0.00006649628,0.00002311202,0.00002506347,0.00004592492,0.00003782706],"domain_scores_gemma":[0.9997252,0.0001462976,0.0000514685,0.00002408246,0.00002394284,0.0000290522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002390952,0.0000478096,0.0001448092,0.0000332152,0.000003893918,0.00002914671,0.00001268257,0.0001259732,0.9980984,0.00004066272,0.00004272525,0.001181521],"study_design_scores_gemma":[0.000009764779,0.0002873593,0.001633018,0.000004691814,0.000006358324,0.00006561145,0.00001320015,0.0005231592,0.996805,0.00002027029,0.0006286118,0.000002922243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950024,0.002236684,0.0007056343,0.0000882132,0.00003013527,0.00001520495,0.0003702538,0.00003937313,0.001511928],"genre_scores_gemma":[0.9957885,0.0008922661,0.001393716,0.00006010537,0.00001357456,0.00001615549,0.0007464022,0.00001252528,0.001076814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000804379,"threshold_uncertainty_score":0.002284169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00807707434882508,"score_gpt":0.2389344647503691,"score_spread":0.2308573904015441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}