{"id":"W2061606551","doi":"10.1016/j.coph.2004.06.006","title":"Mitochondrial uncoupling proteins as potential targets for pharmacological agents","year":2004,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Uncoupling protein; UCP3; Thermogenin; Thermogenesis; Mitochondrial carrier; Biology; Biochemistry; Uncoupling Agents; Function (biology); Cell biology; Mitochondrion; Bacterial outer membrane; Brown adipose tissue; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003133823,0.0008035856,0.002730308,0.0005925292,0.0001378051,0.0000218287,0.0004167999,0.0007604439,0.001451089],"category_scores_gemma":[0.0001219977,0.0006774146,0.0009727674,0.0004279803,0.0001618227,0.00009665087,0.0002070129,0.001509612,0.0003504735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005010387,"about_ca_system_score_gemma":0.00169456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007777585,"about_ca_topic_score_gemma":1.815848e-7,"domain_scores_codex":[0.9959466,0.0002440656,0.001354672,0.001090593,0.0003778276,0.0009861764],"domain_scores_gemma":[0.9984271,0.0001535886,0.0005777541,0.0002352215,0.0001555284,0.0004508332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007200685,0.002136399,0.000001993514,0.05528373,0.0008521031,0.0001166455,0.00008439609,0.00003541127,0.0003288492,0.0002909985,0.04823452,0.8919149],"study_design_scores_gemma":[0.008735155,0.0004506418,0.000002600025,0.008276119,0.003370146,0.0002239186,0.000004060333,0.00005101622,0.00008017437,0.0001899325,0.9780644,0.0005518258],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000242544,0.9165794,0.0007590683,0.0001778233,0.07192935,0.01023432,0.0001331252,0.0001123506,0.00005026083],"genre_scores_gemma":[0.00001768271,0.978672,0.0007507214,0.0000964811,0.01445443,0.004219205,0.001374203,0.0001196356,0.0002955859],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9298299,"threshold_uncertainty_score":0.9995677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1407214589214393,"score_gpt":0.4814563360072646,"score_spread":0.3407348770858253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}