{"id":"W2061616584","doi":"10.1262/jrd.20094","title":"Cell Growth of Ovarian Cancer Cells is Stimulated by Xenoestrogens through an Estrogen-Dependent Pathway, but Their Stimulation of Cell Growth Appears not to be Involved in the Activation of the Mitogen-Activated Protein Kinases ERK-1 and p38","year":2009,"lang":"en","type":"article","venue":"Journal of Reproduction and Development","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; Women's Health Research Institute; University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; Faculty of Medicine, University of British Columbia","keywords":"MAPK/ERK pathway; Cell growth; Estrogen receptor; Biology; Endocrinology; Estrogen; Internal medicine; Kinase; Cancer research; Cell biology; Chemistry; Cancer; Medicine; Biochemistry; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000421078,0.0001662979,0.0002326491,0.00007699518,0.00007026775,0.00001308792,0.0001342282,0.0001329618,0.000002293253],"category_scores_gemma":[0.00003571859,0.0001057803,0.00005672474,0.0001995845,0.00005494994,0.00003289317,0.00003679334,0.0001581867,6.995276e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000313062,"about_ca_system_score_gemma":0.0001868326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000095682,"about_ca_topic_score_gemma":0.000003044904,"domain_scores_codex":[0.9986271,0.0001618807,0.0005299719,0.0002702907,0.0002748359,0.0001359247],"domain_scores_gemma":[0.9988284,0.00001319391,0.0005963303,0.0002088894,0.0002986895,0.00005447106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005784908,0.0003105147,0.00136771,0.00005064985,0.00005687125,7.809314e-7,0.002403653,0.0003622509,0.9939438,0.000006948841,0.0001099542,0.0008084382],"study_design_scores_gemma":[0.0009930886,0.0006745962,0.005671377,0.00006730144,0.00002411564,0.000009792615,0.0007051741,0.00001735927,0.9915173,0.0000338262,0.0001741629,0.0001119092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979453,0.0007061244,0.000185444,0.0005418297,0.00007798673,0.0005136391,0.00001564906,0.000002589298,0.00001142502],"genre_scores_gemma":[0.998394,0.0003911639,0.0010078,0.0001084402,0.0000394042,0.00000528548,0.00001450243,0.00001105281,0.00002831138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004303666,"threshold_uncertainty_score":0.4313597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01467732265938254,"score_gpt":0.2403106281333545,"score_spread":0.225633305473972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}