{"id":"W2061616584","doi":"10.1262/jrd.20094","title":"Cell Growth of Ovarian Cancer Cells is Stimulated by Xenoestrogens through an Estrogen-Dependent Pathway, but Their Stimulation of Cell Growth Appears not to be Involved in the Activation of the Mitogen-Activated Protein Kinases ERK-1 and p38","year":2009,"lang":"en","type":"article","venue":"Journal of Reproduction and Development","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; Women's Health Research Institute; University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; Faculty of Medicine, University of British Columbia","keywords":"MAPK/ERK pathway; Cell growth; Estrogen receptor; Biology; Endocrinology; Estrogen; Internal medicine; Kinase; Cancer research; Cell biology; Chemistry; Cancer; Medicine; Biochemistry; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005569972,0.0002821416,0.0002268642,0.0002578303,0.0001710627,0.0001602159,0.00007158409,0.0001373147,0.002012544],"category_scores_gemma":[0.00007628332,0.000103801,0.0002589651,0.0002819435,0.0001261786,0.000112245,0.0001558127,0.0002562856,0.0005304519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573762,"about_ca_system_score_gemma":0.0001756762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009338195,"about_ca_topic_score_gemma":0.001554438,"domain_scores_codex":[0.9999247,0.000008902214,0.000006057111,0.00001290469,0.00003104533,0.00001643036],"domain_scores_gemma":[0.9999456,0.00001573098,0.00001072062,0.000008076991,0.00001216067,0.000007692946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001746601,0.00008877167,0.001066,0.000132839,0.000009391169,0.0001043683,0.00004265901,0.00007585307,0.990983,0.0001208468,0.0001403887,0.007061322],"study_design_scores_gemma":[0.00003898534,0.000805526,0.05613735,0.00002425445,0.00002800579,0.000707446,0.0001284289,0.0008658036,0.9238314,0.0001568978,0.01726623,0.000009694764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979311,0.008708227,0.003208956,0.0002545556,0.00006437697,0.00006025194,0.001633347,0.00008899752,0.006670373],"genre_scores_gemma":[0.9773513,0.00981908,0.00308162,0.0001034389,0.00002426128,0.0001060781,0.002413436,0.00001639932,0.007084515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002012544,"threshold_uncertainty_score":0.006732643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01467732265938254,"score_gpt":0.2403106281333545,"score_spread":0.225633305473972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}