{"id":"W2061656751","doi":"10.1016/j.yexcr.2006.10.012","title":"Sodium 4-phenylbutyrate upregulates ENaC and sodium absorption in T84 cells","year":2006,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Cystic Fibrosis Foundation","keywords":"Biology; Epithelial sodium channel; Sodium; Phenylbutyrate; Internal medicine; Absorption (acoustics); Endocrinology; Cell biology; Biophysics; Materials science; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000314723,0.0001310795,0.0001005002,0.000106425,0.0001101496,0.00004485575,0.0001093226,0.0001514719,0.00007588417],"category_scores_gemma":[0.000001695049,0.0001316551,0.00004122814,0.0001179374,0.0001518631,0.000009953541,0.00007276839,0.0001251552,0.00002869753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000371747,"about_ca_system_score_gemma":0.00003347334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002807541,"about_ca_topic_score_gemma":0.000065198,"domain_scores_codex":[0.9987136,0.00007959622,0.0001899402,0.0003695489,0.0002688085,0.0003785475],"domain_scores_gemma":[0.9996624,0.000009452725,0.00002800255,0.0001780696,0.00005454612,0.00006750518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001523597,0.0001358173,0.001199777,0.00001731097,0.000002659853,0.000005617524,0.000118245,0.00006061287,0.9973319,0.00007400505,0.0007903101,0.0001114194],"study_design_scores_gemma":[0.0007535717,0.0001945804,0.004790381,0.000008487871,0.000001247532,0.000001954835,0.0004335074,0.0002091215,0.9890591,0.0001556905,0.004247454,0.0001448986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922135,0.002459202,0.00006561677,0.00006037196,0.0000927822,0.0002415912,0.000005029548,0.000009869411,0.004852014],"genre_scores_gemma":[0.9925221,0.0001172972,0.0001105558,0.00001583,0.0002394638,0.00004043186,0.0001914157,0.00002274975,0.006740161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00827276,"threshold_uncertainty_score":0.5368741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01753024534983488,"score_gpt":0.2925727179884262,"score_spread":0.2750424726385913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}