{"id":"W2061735505","doi":"10.1074/jbc.m102394200","title":"Identification and Characterization of S2V, a Novel Putative Siglec That Contains Two V Set Ig-like Domains and Recruits Protein-tyrosine Phosphatases SHPs","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Biotechnology Research Institute","funders":"","keywords":"Immunoreceptor tyrosine-based activation motif; Protein tyrosine phosphatase; Biology; Sialic acid; SH2 domain; Tyrosine; Proto-oncogene tyrosine-protein kinase Src; Biochemistry; Transmembrane protein; Immunoglobulin superfamily; Tyrosine phosphorylation; Immunoglobulin domain; Receptor tyrosine kinase; Transmembrane domain; Molecular biology; Signal transduction; Cell biology; Amino acid; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219146,0.0003736186,0.0002369073,0.0002546947,0.0001698233,0.0005057477,0.0001760758,0.0003095064,0.0004791945],"category_scores_gemma":[0.0001316981,0.0001015607,0.0003128591,0.000249768,0.0002137762,0.0002340519,0.0002651724,0.0002757745,0.0004715331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002976081,"about_ca_system_score_gemma":0.00034372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005648125,"about_ca_topic_score_gemma":0.0007805185,"domain_scores_codex":[0.9999112,0.00001232322,0.000004590795,0.00001476896,0.00003298004,0.00002403433],"domain_scores_gemma":[0.9999262,0.000007885643,0.0000137721,0.000007141124,0.00001687679,0.00002805099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006208096,0.00002959993,0.00171366,0.00003734228,0.000008425398,0.0002310092,0.00002564677,0.0001580146,0.9944438,0.000184321,0.0001240662,0.002982061],"study_design_scores_gemma":[0.00007368172,0.001061897,0.05321935,0.00002616206,0.00008310307,0.004302172,0.0003573847,0.008408443,0.8838688,0.0005546329,0.04801444,0.00002989843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936655,0.001363348,0.003557158,0.0001358809,0.00002322494,0.00001887328,0.0004452169,0.00002656569,0.0007642256],"genre_scores_gemma":[0.9842387,0.001004317,0.006026142,0.0001011468,0.00002394625,0.00002237573,0.005228645,0.00001770134,0.003337108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005648125,"threshold_uncertainty_score":0.002159297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03328576193190431,"score_gpt":0.2726791192706484,"score_spread":0.2393933573387441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}