{"id":"W2061768488","doi":"10.1128/jb.01991-07","title":"Mutations in the<i>tacF</i>Gene of Clinical Strains and Laboratory Transformants of<i>Streptococcus pneumoniae:</i>Impact on Choline Auxotrophy and Growth Rate","year":2008,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Dental and Craniofacial Research; Dirección General de Investigación Científica y Técnica; European Bioinformatics Institute; Microsoft","keywords":"Biology; Teichoic acid; Streptococcus pneumoniae; Mutant; Phosphocholine; Microbiology; Choline; Auxotrophy; Streptococcus mitis; Gene; Bacteria; Biochemistry; Genetics; Streptococcus; Peptidoglycan; Phospholipid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002217155,0.0004466957,0.0003457069,0.0004752124,0.000187792,0.0003595754,0.0003727151,0.0004686889,0.00182087],"category_scores_gemma":[0.0005769064,0.0001573858,0.0004469199,0.000388519,0.0003091187,0.000123775,0.0002832534,0.0005889755,0.0005569665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003474119,"about_ca_system_score_gemma":0.0003686348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002743695,"about_ca_topic_score_gemma":0.001677519,"domain_scores_codex":[0.9994683,0.00009901176,0.0001002127,0.0001030451,0.0001288396,0.0001007209],"domain_scores_gemma":[0.9996394,0.00009437589,0.0001024367,0.00004737265,0.00003758545,0.00007887716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002108463,0.0001028455,0.0008325872,0.0000247113,0.00001048958,0.0001776303,0.00003605923,0.00004203542,0.9972534,0.00005221091,0.00005777656,0.001199419],"study_design_scores_gemma":[0.00004152166,0.000742522,0.01884671,0.00001579599,0.00005887022,0.002208553,0.0001485358,0.000903364,0.9753784,0.00003278844,0.001601802,0.00002121219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972378,0.000208989,0.0009505191,0.0000782311,0.00001828892,0.00004243355,0.0006641983,0.00006949183,0.0007299196],"genre_scores_gemma":[0.9957556,0.0001779653,0.001991589,0.00003619107,0.000008292689,0.00003629881,0.001049179,0.00008144639,0.0008634149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002743695,"threshold_uncertainty_score":0.006091416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03514314789896591,"score_gpt":0.3457977113425449,"score_spread":0.3106545634435791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}