{"id":"W2061817827","doi":"10.1016/j.cllc.2014.07.005","title":"Gastric Acid Suppression Is Associated With Decreased Erlotinib Efficacy in Non–Small-Cell Lung Cancer","year":2014,"lang":"en","type":"article","venue":"Clinical Lung Cancer","topic":"Metastasis and carcinoma case studies","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Alberta Cancer Foundation; University of Alberta","funders":"","keywords":"Erlotinib; Medicine; Internal medicine; Lung cancer; Concomitant; Oncology; Erlotinib Hydrochloride; Population; Adenocarcinoma; Retrospective cohort study; Cancer; Epidermal growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003306117,0.0002239,0.0002638791,0.0006741452,0.0004011637,0.0005558366,0.0002735289,0.0004828769,0.002069324],"category_scores_gemma":[0.001631951,0.0001576676,0.0003989261,0.0006866967,0.0005767752,0.0003247218,0.0002284825,0.0003391369,0.0001977902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000330868,"about_ca_system_score_gemma":0.0001818701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002024069,"about_ca_topic_score_gemma":0.002061845,"domain_scores_codex":[0.9997481,0.00007272384,0.00003546282,0.00004156967,0.00004550729,0.00005666418],"domain_scores_gemma":[0.9992405,0.0003186816,0.0002287799,0.0000602467,0.00005937084,0.00009238871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002347911,0.0002462136,0.9164325,0.000125692,0.0001457836,0.0660768,0.0002820227,0.00008473609,0.005453429,0.0003034487,0.0003279203,0.0081735],"study_design_scores_gemma":[0.00006122322,0.0008153457,0.8760294,0.00002199444,0.0002668335,0.1182472,0.0006626128,0.0004295488,0.001793916,0.0001842861,0.001470541,0.00001715862],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976382,0.0009063769,0.00004114543,0.00005858361,0.000004285813,0.000005935327,0.00004197248,0.000003066503,0.001300332],"genre_scores_gemma":[0.9996372,0.0001722029,0.00001884032,0.00001124108,0.000009401595,0.000001094786,0.00003685938,7.534237e-7,0.0001123471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002069324,"threshold_uncertainty_score":0.006922603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03680941315444405,"score_gpt":0.3661857580732465,"score_spread":0.3293763449188024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}