{"id":"W2061820209","doi":"10.1097/01.tp.0000153158.91683.34","title":"Efficacy and Safety Outcomes Among De Novo Renal Transplant Recipients Managed by C2 Monitoring of Cyclosporine A Microemulsion: Results of a 12-Month, Randomized, Multicenter Study","year":2005,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Renal function; Azathioprine; Clinical endpoint; Urology; Incidence (geometry); Internal medicine; Gastroenterology; Transplantation; Multicenter trial; Randomized controlled trial; Mycophenolate; Prospective cohort study; Surgery; Multicenter study","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003028306,0.001025958,0.002325698,0.0003521629,0.0004960652,0.001094608,0.0006653621,0.001434554,0.001300336],"category_scores_gemma":[0.00206028,0.0004683174,0.001835734,0.0004207136,0.0008954779,0.000884496,0.0004443708,0.001299005,0.0002358327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006629785,"about_ca_system_score_gemma":0.0006323933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003722746,"about_ca_topic_score_gemma":0.0004867736,"domain_scores_codex":[0.9984937,0.0008095889,0.0001405161,0.0002422082,0.0001484616,0.0001655231],"domain_scores_gemma":[0.9969602,0.0006325974,0.001127941,0.0002481714,0.000169474,0.0008615061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9076787,0.01686317,0.05392511,0.0002463294,0.002039523,0.0001115555,0.0001343232,0.000277752,0.004701806,0.0000357074,0.000202478,0.01378353],"study_design_scores_gemma":[0.4020255,0.429745,0.1610393,0.00005471647,0.00286091,0.0002832751,0.0001282598,0.001209847,0.001998705,0.00009930557,0.0004927757,0.00006248811],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991991,0.0004492347,0.00005741989,0.00002620566,0.00001291205,0.000123408,0.00005452845,0.000003885081,0.00007338403],"genre_scores_gemma":[0.9986798,0.0003082214,0.0001970141,0.0001027,0.0001019264,0.0002509476,0.0002245795,0.000002838125,0.0001320268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003028306,"threshold_uncertainty_score":0.01601541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0134122020078267,"score_gpt":0.2866613356940779,"score_spread":0.2732491336862513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}