{"id":"W2061827620","doi":"10.1097/ccm.0b013e31822f09d7","title":"Mechanical stress induces lung fibrosis by epithelial–mesenchymal transition*","year":2011,"lang":"en","type":"article","venue":"Critical Care Medicine","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Epithelial–mesenchymal transition; Medicine; Lung; Mechanical ventilation; Fibrosis; Pathology; Vimentin; Pulmonary fibrosis; Hydroxyproline; Mesenchymal stem cell; Internal medicine; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001433047,0.0004227941,0.0002729716,0.0001607457,0.0001603321,0.0001827224,0.0001077772,0.0004023945,0.001675693],"category_scores_gemma":[0.0001142659,0.0001376268,0.0003552691,0.0001036545,0.000244223,0.0001547011,0.0002699742,0.0005805591,0.0002841441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001176904,"about_ca_system_score_gemma":0.00008913021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001061458,"about_ca_topic_score_gemma":0.0001830129,"domain_scores_codex":[0.999818,0.00004396902,0.00001400259,0.00002605068,0.00004894454,0.00004907686],"domain_scores_gemma":[0.9998841,0.00001974919,0.00004532083,0.000009467808,0.00000989921,0.0000313992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005464266,0.0001521597,0.001314705,0.0001139604,0.00001228635,0.0003498154,0.0000171655,0.00002985244,0.9955475,0.00002885068,0.00005287473,0.001834351],"study_design_scores_gemma":[0.0002576151,0.01743766,0.1659383,0.00007595911,0.0001011394,0.005708937,0.0002691893,0.001247018,0.8052855,0.0002011193,0.003459175,0.00001831791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955708,0.002894313,0.0006287236,0.00008981905,0.00002977319,0.00005006359,0.00009142799,0.00002525497,0.0006197786],"genre_scores_gemma":[0.9973902,0.001211635,0.0004732416,0.00007625057,0.00002489671,0.00006287581,0.0001615357,0.000002700125,0.0005967594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001675693,"threshold_uncertainty_score":0.005605757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03548335051155822,"score_gpt":0.308522867583108,"score_spread":0.2730395170715498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}