{"id":"W2061827620","doi":"10.1097/ccm.0b013e31822f09d7","title":"Mechanical stress induces lung fibrosis by epithelial–mesenchymal transition*","year":2011,"lang":"en","type":"article","venue":"Critical Care Medicine","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Epithelial–mesenchymal transition; Medicine; Lung; Mechanical ventilation; Fibrosis; Pathology; Vimentin; Pulmonary fibrosis; Hydroxyproline; Mesenchymal stem cell; Internal medicine; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002383643,0.0003033132,0.0006161568,0.0001321186,0.0001327426,0.00001067151,0.0001671818,0.0002915292,0.005798304],"category_scores_gemma":[0.0004374644,0.0002270205,0.0001512607,0.0002179284,0.0004166059,0.0001340733,0.00003734741,0.0004432622,0.00006064196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006280448,"about_ca_system_score_gemma":0.0001135621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007784592,"about_ca_topic_score_gemma":0.000004980782,"domain_scores_codex":[0.99769,0.00008614964,0.0005025453,0.0005089916,0.0006652983,0.0005470707],"domain_scores_gemma":[0.9982638,0.0001341349,0.00003757481,0.0004116042,0.0003658693,0.0007870141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001612175,0.001203827,0.003541963,0.003587046,0.0002519288,0.002404569,0.02123332,1.326659e-7,0.8604513,0.03362355,0.03980917,0.03228103],"study_design_scores_gemma":[0.006317602,0.007898089,0.001945283,0.001631797,0.00181912,0.000322719,0.03940002,0.0001026139,0.9166138,0.002381915,0.02066611,0.0009009374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9308062,0.007139749,0.01921465,0.01079199,0.002298082,0.001161816,0.0003771599,0.00051725,0.02769312],"genre_scores_gemma":[0.9943641,0.00003117391,0.00115956,0.003218508,0.0007444551,0.0000502638,0.0001816158,0.00004851368,0.0002017399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06355799,"threshold_uncertainty_score":0.9951105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03548335051155822,"score_gpt":0.308522867583108,"score_spread":0.2730395170715498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}