{"id":"W2061831178","doi":"10.1016/j.nicl.2014.11.015","title":"Basal forebrain atrophy correlates with amyloid β burden in Alzheimer's disease","year":2014,"lang":"en","type":"article","venue":"NeuroImage Clinical","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Health and Medical Research Council; National Institutes of Health; Genentech; IXICO; Servier; Eisai; Northern California Institute for Research and Education; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of Queensland; Judith Jane Mason and Harold Stannett Williams Memorial Foundation; Synarc; Alzheimer's Disease Neuroimaging Initiative; Medical Research Council; Meso Scale Diagnostics; University of Melbourne; F. Hoffmann-La Roche; Biogen; Pfizer; BioClinica; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Eli Lilly and Company; Medpace; Foundation for the National Institutes of Health","keywords":"Basal forebrain; Cholinergic neuron; Neurodegeneration; Pittsburgh compound B; Forebrain; Atrophy; Psychology; Basal (medicine); Pathology; Internal medicine; Neuroscience; Alzheimer's disease; Cholinergic; Medicine; Disease; Central nervous system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003090792,0.000293614,0.0003025987,0.0009683754,0.0002730424,0.0005860048,0.0001740675,0.0002795154,0.00102151],"category_scores_gemma":[0.001068788,0.0001850866,0.0001680101,0.000350181,0.0003355259,0.0002768892,0.0003634643,0.0003921156,0.00022412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631613,"about_ca_system_score_gemma":0.0001667838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00555433,"about_ca_topic_score_gemma":0.004951817,"domain_scores_codex":[0.9998702,0.00002611527,0.00001875667,0.00003553138,0.00003351573,0.00001592474],"domain_scores_gemma":[0.9993278,0.00006482254,0.0003589072,0.00004682093,0.0001019351,0.00009972692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007914777,0.00007977512,0.9786155,0.00003764018,0.0001627105,0.0004880968,0.0003423065,0.0001533293,0.01297859,0.00005487117,0.000184166,0.006111472],"study_design_scores_gemma":[0.00000214049,0.00003725127,0.9993642,0.000003784029,0.00001102129,0.0002834223,0.00004363941,0.00005587616,0.000125185,0.00003973573,0.00003230495,0.000001559311],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990758,0.0003268279,0.00008098163,0.00002098124,0.000001938115,0.000003629438,0.00007752662,0.000006042373,0.0004062734],"genre_scores_gemma":[0.9993936,0.0001668682,0.0001077963,0.00001203633,0.000004375707,0.000003413294,0.000142607,0.000001775637,0.0001675389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00555433,"threshold_uncertainty_score":0.01104397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03720728407440931,"score_gpt":0.3589838695855979,"score_spread":0.3217765855111885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}