{"id":"W2061831178","doi":"10.1016/j.nicl.2014.11.015","title":"Basal forebrain atrophy correlates with amyloid β burden in Alzheimer's disease","year":2014,"lang":"en","type":"article","venue":"NeuroImage Clinical","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Health and Medical Research Council; National Institutes of Health; Genentech; IXICO; Servier; Eisai; Northern California Institute for Research and Education; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of Queensland; Judith Jane Mason and Harold Stannett Williams Memorial Foundation; Synarc; Alzheimer's Disease Neuroimaging Initiative; Medical Research Council; Meso Scale Diagnostics; University of Melbourne; F. Hoffmann-La Roche; Biogen; Pfizer; BioClinica; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Eli Lilly and Company; Medpace; Foundation for the National Institutes of Health","keywords":"Basal forebrain; Cholinergic neuron; Neurodegeneration; Pittsburgh compound B; Forebrain; Atrophy; Psychology; Basal (medicine); Pathology; Internal medicine; Neuroscience; Alzheimer's disease; Cholinergic; Medicine; Disease; Central nervous system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008174427,0.0001921335,0.0003854777,0.0001265881,0.00005308157,0.00004283252,0.0001566936,0.00007748534,0.0003952693],"category_scores_gemma":[0.001183333,0.0001444045,0.0001701135,0.0002288378,0.0003589728,0.0001096821,0.0001153662,0.0006716574,0.0003324635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001277947,"about_ca_system_score_gemma":0.0001494097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001636971,"about_ca_topic_score_gemma":0.000008162183,"domain_scores_codex":[0.9975907,0.0003778977,0.000484881,0.0005902427,0.0004974749,0.0004588441],"domain_scores_gemma":[0.9981419,0.0006759947,0.00007382893,0.000436824,0.0001160298,0.0005553605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002316135,0.0005529308,0.9637926,0.00002422146,0.00006094888,0.0009292378,0.00002131626,0.00000566492,0.0001833464,0.00008001418,0.001418655,0.03061494],"study_design_scores_gemma":[0.005598053,0.002810305,0.9794447,0.00009394907,0.0002264493,0.00001423275,0.00002491911,0.00537824,0.00007147599,0.0003069841,0.005865843,0.0001647777],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866036,0.00009464365,0.0002836406,0.00442528,0.0001471335,0.0006187594,0.000006478325,0.00006672998,0.007753742],"genre_scores_gemma":[0.9955179,0.00004551923,0.0003144309,0.003023715,0.0004513168,0.00003931625,0.00003484942,0.00004260386,0.0005303529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03045017,"threshold_uncertainty_score":0.5888644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03720728407440931,"score_gpt":0.3589838695855979,"score_spread":0.3217765855111885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}