{"id":"W2061909637","doi":"10.1158/1538-7445.am2012-4028","title":"Abstract 4028: Therapeutic relevance of two novel cancer candidate genes, <i>RASAL2</i> and <i>NENF</i>, activated by DNA hypomethylation","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Cancer research; Cancer; Metastasis; DNA methylation; Cancer cell; Viability assay; Molecular biology; Cell culture; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001384209,0.0002792099,0.0003247035,0.0001331727,0.000121074,0.0002445861,0.0001464113,0.0003329161,0.00341041],"category_scores_gemma":[0.0001071725,0.0000798759,0.0002032215,0.00009421819,0.0001556199,0.0001009278,0.00008328753,0.0005546361,0.0006033381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002731351,"about_ca_system_score_gemma":0.0002315422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003954247,"about_ca_topic_score_gemma":0.0005327132,"domain_scores_codex":[0.9999127,0.00001184358,0.000007499673,0.0000178811,0.000029693,0.00002038976],"domain_scores_gemma":[0.9999495,0.000008676213,0.00001388624,0.000004630915,0.000007823264,0.00001555314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006697685,0.0001222418,0.0002738939,0.00007501702,0.00001272925,0.0001014795,0.00001011112,0.0001153741,0.9932468,0.0001090766,0.0003626032,0.004900776],"study_design_scores_gemma":[0.0002764464,0.002675203,0.00447125,0.00001226666,0.00007991575,0.0007004814,0.00002684988,0.001043238,0.9807315,0.00008934856,0.009886769,0.000006505111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850899,0.004015461,0.003093706,0.0005900448,0.0002036071,0.0001904866,0.001101792,0.0002399206,0.005475062],"genre_scores_gemma":[0.9916631,0.001005283,0.00157115,0.00019312,0.00003406423,0.0001138548,0.0009067347,0.00004082757,0.004471796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00341041,"threshold_uncertainty_score":0.01140893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05603029276172602,"score_gpt":0.3936116377663677,"score_spread":0.3375813450046417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}