{"id":"W2061949562","doi":"10.1002/psc.896","title":"Viral peptide immunogens: current challenges and opportunities","year":2007,"lang":"en","type":"review","venue":"Journal of Peptide Science","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Variation Biotechnologies (Canada); Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Epitope; Immunogen; Immunogenicity; Virology; Peptide vaccine; Antigen; Peptide; Biology; CTL*; Major histocompatibility complex; Vaccination; MHC class I; Antigen processing; Immunology; CD8; Antibody; Monoclonal antibody; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004368044,0.0005190537,0.001786734,0.001337667,0.0004216686,0.00009187649,0.001254325,0.0003246264,0.0001244439],"category_scores_gemma":[0.0003339987,0.0003669942,0.0006017864,0.000257067,0.00234264,0.0006270489,0.0002716534,0.00130271,0.00008702042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001894043,"about_ca_system_score_gemma":0.0016632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004898201,"about_ca_topic_score_gemma":0.000001159705,"domain_scores_codex":[0.9967182,0.0004772094,0.001476159,0.000379114,0.0002355819,0.0007137632],"domain_scores_gemma":[0.9968601,0.0005513675,0.001650115,0.0004627233,0.0003989853,0.00007668871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008767373,0.000075584,3.289933e-7,0.001058665,0.0002076661,0.00003258847,0.0004737221,4.895232e-8,0.001187525,0.000698132,0.0004108699,0.9957672],"study_design_scores_gemma":[0.0004075817,0.0004880439,0.0000403402,0.008620267,0.0002923595,0.003477817,0.0004446332,5.059536e-8,0.0002555203,0.00007387483,0.9855228,0.0003767237],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004320211,0.9957632,0.00001569821,0.00006377498,0.002575078,0.00021829,0.00001489046,0.00001830579,0.0008987586],"genre_scores_gemma":[0.00009511236,0.9976859,0.00009115654,0.00003977797,0.0001490018,0.000005197255,0.000005376072,0.00003400354,0.001894461],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9953905,"threshold_uncertainty_score":0.9998782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1586277665109037,"score_gpt":0.3682328199435962,"score_spread":0.2096050534326925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}