{"id":"W2062008821","doi":"10.1074/jbc.m212168200","title":"Substrate Specificity of Human Endonuclease III (hNTH1)","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Substrate specificity; Endonuclease; Substrate (aquarium); Chemistry; Molecular biology; Biology; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004396629,0.0001632011,0.0003059418,0.00001700621,0.00004266539,0.00001017579,0.0002856249,0.0002794887,0.0003870751],"category_scores_gemma":[0.0002594656,0.0001235738,0.0002815157,0.00006655051,0.000150696,0.000003525483,0.00005210802,0.0002083929,0.000002434779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001750846,"about_ca_system_score_gemma":0.00006331486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001191753,"about_ca_topic_score_gemma":3.350353e-7,"domain_scores_codex":[0.9987991,0.00006963895,0.0005500014,0.0002063217,0.0001615775,0.0002134028],"domain_scores_gemma":[0.9989112,0.00001793576,0.0004801847,0.0002520808,0.000179692,0.0001588957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001107457,0.0001853381,0.001889623,0.00001825044,0.00005079286,0.00003283961,0.00000616314,0.000007100668,0.9971188,0.0001686555,0.0003246512,0.00008707403],"study_design_scores_gemma":[0.0006771159,0.0004596348,0.0007452301,0.00001659965,0.00001656081,0.0002032735,0.00009908576,0.000001013006,0.9932975,0.0005889263,0.0037566,0.0001384142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915279,0.0004622202,0.0001552932,0.00001603049,0.00006695525,0.00004515376,0.000008823999,0.000005714624,0.007711935],"genre_scores_gemma":[0.9984674,0.00012521,0.0008321117,0.00004433663,0.0002073365,0.000001113572,0.00001107223,0.00001080077,0.0003006178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007411317,"threshold_uncertainty_score":0.5039192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02425093615750353,"score_gpt":0.2545635532416886,"score_spread":0.2303126170841851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}