{"id":"W2062008821","doi":"10.1074/jbc.m212168200","title":"Substrate Specificity of Human Endonuclease III (hNTH1)","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Substrate specificity; Endonuclease; Substrate (aquarium); Chemistry; Molecular biology; Biology; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003372476,0.0004057522,0.0003136999,0.0001779888,0.0001290496,0.0003644068,0.0002038891,0.0003083813,0.001933842],"category_scores_gemma":[0.0004282448,0.0001682039,0.0002234417,0.0001952352,0.0001285422,0.0001593,0.0002206836,0.0003102042,0.001953848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003565683,"about_ca_system_score_gemma":0.0002503385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001100703,"about_ca_topic_score_gemma":0.001098367,"domain_scores_codex":[0.9995621,0.00007298167,0.00003596055,0.0001713968,0.00009994665,0.00005758116],"domain_scores_gemma":[0.999751,0.00004721701,0.00004537884,0.00003480992,0.00007872357,0.00004271172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001400204,0.00001161211,0.001061289,0.00009197004,0.000008031157,0.00004337634,0.00001455894,0.00009626518,0.9910857,0.00008365523,0.0001676915,0.007195848],"study_design_scores_gemma":[0.000006046606,0.0001200795,0.004900571,0.000007330893,0.000009630527,0.0008328217,0.00001546619,0.0004203229,0.9871314,0.00004473145,0.006504993,0.000006627016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9472466,0.01518712,0.02710499,0.0001982786,0.0001319929,0.00009568743,0.002040207,0.000393724,0.007601462],"genre_scores_gemma":[0.9692845,0.003328844,0.01443028,0.0001222561,0.00002294528,0.0000445167,0.00484687,0.00006650349,0.007853195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001933842,"threshold_uncertainty_score":0.006469369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02425093615750353,"score_gpt":0.2545635532416886,"score_spread":0.2303126170841851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}