{"id":"W2062029351","doi":"10.1021/bi050846l","title":"A Bivalent Dissectional Analysis of the High-Affinity Interactions between Cdc42 and the Cdc42/Rac Interactive Binding Domains of Signaling Kinases in <i>Candida albicans</i>","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"CDC42; Candida albicans; Bivalent (engine); Kinase; Chemistry; Cell biology; Biochemistry; Biology; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002749434,0.000238504,0.000530109,0.00009951505,0.0001467681,0.00003136309,0.0003596282,0.0001368845,0.0006427849],"category_scores_gemma":[0.0003959087,0.0001688625,0.0003919533,0.0007483328,0.0004573614,0.00008623548,0.0001785771,0.0003940752,6.302827e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001989359,"about_ca_system_score_gemma":0.00008045317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004109979,"about_ca_topic_score_gemma":0.000131833,"domain_scores_codex":[0.9984204,0.00005896233,0.0006312335,0.0003654088,0.0003034155,0.0002206084],"domain_scores_gemma":[0.9974093,0.001457212,0.0004903114,0.0004902206,0.00008031554,0.00007258655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002042587,0.0001589162,0.03109074,0.0001352352,0.0009046815,0.000001391034,0.0005071756,0.0002566502,0.9663407,0.00002394057,0.00003376804,0.000342536],"study_design_scores_gemma":[0.00066943,0.000003458141,0.004391621,0.0002194382,0.0008621741,0.000005845658,0.001471484,0.0002952338,0.9917603,0.00003885445,0.0001108309,0.0001713252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965152,0.0001337541,0.00001167973,0.0004195074,0.00003665025,0.00006436528,0.0004831111,0.00001663117,0.002319059],"genre_scores_gemma":[0.9991841,0.00003246273,0.00005399286,0.00001859069,0.0001944923,0.00003322712,0.00008242636,0.00001472002,0.0003859368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02669912,"threshold_uncertainty_score":0.7038044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008987508926833773,"score_gpt":0.2392669011375892,"score_spread":0.2302793922107554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}