{"id":"W2062044568","doi":"10.1016/j.jss.2010.05.039","title":"In Utero Gene Delivery Using Chitosan-DNA Nanoparticles in Mice","year":2010,"lang":"en","type":"article","venue":"Journal of Surgical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Child and Family Research Institute; Cystic Fibrosis Foundation","keywords":"Gene delivery; Transfection; Reporter gene; Transgene; In utero; Genetic enhancement; Amniotic fluid; Molecular biology; Biology; Chitosan; Viral vector; In vitro; Naked DNA; Fetus; Chemistry; Gene expression; Gene; Biochemistry; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004911293,0.001096214,0.0005247099,0.001401592,0.0004529374,0.0006771358,0.0008807032,0.00139643,0.002102058],"category_scores_gemma":[0.0002389915,0.0006728137,0.0007654852,0.0003416321,0.001113078,0.0007526313,0.0003850886,0.001867175,0.0008027481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009378408,"about_ca_system_score_gemma":0.000803871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002238887,"about_ca_topic_score_gemma":0.002903912,"domain_scores_codex":[0.9995345,0.0000512094,0.00003403087,0.0001597647,0.0001047292,0.0001157416],"domain_scores_gemma":[0.9994736,0.00007678555,0.0002211191,0.00007078351,0.00003800649,0.0001197293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005025942,0.0001137379,0.00009826235,0.00005633795,0.00001285157,0.0001342653,0.00004560237,0.0001408558,0.9964115,0.0004909956,0.0001134207,0.001879601],"study_design_scores_gemma":[0.00004906361,0.0005469021,0.0003843164,0.000007563046,0.00003644769,0.0001985354,0.0000207313,0.0004340376,0.9960946,0.0000706923,0.00214835,0.000008768896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9624684,0.005098986,0.01865874,0.001275454,0.0004640032,0.0003279642,0.001731922,0.001184589,0.008789956],"genre_scores_gemma":[0.9550521,0.003757484,0.01165389,0.0003456689,0.00008690408,0.0002928491,0.0008494072,0.0002481032,0.02771368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002238887,"threshold_uncertainty_score":0.007032037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05608275529123845,"score_gpt":0.3805747837331485,"score_spread":0.32449202844191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}