{"id":"W2062070280","doi":"10.1053/j.gastro.2005.11.012","title":"Antisense Inhibition of Entamoeba histolytica Cysteine Proteases Inhibits Colonic Mucus Degradation","year":2006,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Entamoeba histolytica; Proteases; Mucus; Microbiology; Chemistry; Cysteine; Mucin; Degradation (telecommunications); Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001788198,0.0003748312,0.0003579154,0.0002190493,0.0002003379,0.0003213768,0.0001764678,0.0003969203,0.001742142],"category_scores_gemma":[0.0002063483,0.0002267115,0.0002747652,0.0001329276,0.0003673492,0.0002018492,0.0001635763,0.0008808387,0.0002906362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002767541,"about_ca_system_score_gemma":0.0002781184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007370313,"about_ca_topic_score_gemma":0.001239287,"domain_scores_codex":[0.9998184,0.00002265271,0.00001877392,0.00002820154,0.00003904211,0.00007290771],"domain_scores_gemma":[0.9998304,0.00005603171,0.00003119152,0.00001708649,0.00001752317,0.00004776302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003890515,0.0000495816,0.00007208627,0.0000271572,0.000005265624,0.00002482715,0.000009863991,0.00003858772,0.9982699,0.00006593121,0.00004152852,0.001006143],"study_design_scores_gemma":[0.0001009997,0.001338409,0.002035444,0.000004790296,0.00001713893,0.0001147546,0.0000479315,0.0006673604,0.9944331,0.00005642597,0.001178831,0.000004670003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936994,0.002007207,0.002100464,0.0002422408,0.0001542925,0.0000340096,0.0001534205,0.00008126363,0.001527657],"genre_scores_gemma":[0.9949757,0.00107631,0.001369218,0.00007903368,0.0000252696,0.00002249652,0.0001761163,0.00001341625,0.002262544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001742142,"threshold_uncertainty_score":0.005828083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00687509156839032,"score_gpt":0.2272681334266511,"score_spread":0.2203930418582608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}