{"id":"W2062070280","doi":"10.1053/j.gastro.2005.11.012","title":"Antisense Inhibition of Entamoeba histolytica Cysteine Proteases Inhibits Colonic Mucus Degradation","year":2006,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Entamoeba histolytica; Proteases; Mucus; Microbiology; Chemistry; Cysteine; Mucin; Degradation (telecommunications); Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006836221,0.0001342949,0.000287518,0.0001801191,0.00005653684,0.000003641315,0.00002053665,0.00007713559,0.00008824184],"category_scores_gemma":[0.00002522296,0.0001201218,0.00009194243,0.0001064029,0.0001333405,0.00005970724,0.00002456105,0.00009243693,0.00003271586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001297873,"about_ca_system_score_gemma":0.00003877724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003573912,"about_ca_topic_score_gemma":0.0001793826,"domain_scores_codex":[0.9990016,0.00006142828,0.0003459974,0.0002112059,0.0001282649,0.0002515261],"domain_scores_gemma":[0.9994583,0.0000165342,0.0001733507,0.0001840164,0.0001134319,0.00005434202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001888295,0.002144747,0.8225337,0.0001221589,0.000147659,0.0002381488,0.00003888098,0.00001844682,0.1689293,0.0006894283,0.002379277,0.0008699715],"study_design_scores_gemma":[0.01308634,0.01283655,0.8400673,0.0002436339,0.0006007043,0.002737502,0.00004542336,0.0002987783,0.1283637,0.0003124774,0.00123656,0.0001710256],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970711,0.00005707071,0.0007802834,0.0006219593,0.0001060332,0.0005456668,0.0000263679,0.00005301226,0.0007385057],"genre_scores_gemma":[0.9982988,0.000008549795,0.0006790643,0.0001324585,0.000081246,0.00005574109,0.0002605697,0.00001514186,0.0004683933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04056562,"threshold_uncertainty_score":0.4898427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00687509156839032,"score_gpt":0.2272681334266511,"score_spread":0.2203930418582608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}