{"id":"W2062141943","doi":"10.1093/nar/gkq349","title":"Rapid decay of unstable Leishmania mRNAs bearing a conserved retroposon signature 3′-UTR motif is initiated by a site-specific endonucleolytic cleavage without prior deadenylation","year":2010,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies; Canadian Institutes of Health Research; Université Laval","keywords":"Retroposon; Biology; Cleavage (geology); Untranslated region; Three prime untranslated region; Genetics; Messenger RNA; Molecular biology; Cell biology; Gene; Transposable element; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002006073,0.0002871822,0.0002151914,0.0001409133,0.00009872883,0.0002824304,0.000110464,0.0001565605,0.0005083883],"category_scores_gemma":[0.0001822893,0.0001560569,0.0002424845,0.00008773168,0.0002076343,0.000114573,0.0001716138,0.00029711,0.0002565767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001953241,"about_ca_system_score_gemma":0.0001471429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001920196,"about_ca_topic_score_gemma":0.000330019,"domain_scores_codex":[0.9998754,0.00002069093,0.00001123758,0.00002811968,0.00003622641,0.0000282981],"domain_scores_gemma":[0.9998032,0.00004053415,0.00006835721,0.00002616154,0.00002859693,0.00003309463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002069875,0.000002196923,0.0001329729,0.000007692736,0.000001366606,0.00002501842,0.000006340872,0.00001438521,0.9995246,0.00002923516,0.000003448374,0.0002321071],"study_design_scores_gemma":[0.000005915219,0.0001458848,0.005376645,0.000003098906,0.000005920575,0.0003185248,0.00002240622,0.0006299284,0.9927396,0.0000436202,0.0007049476,0.000003471235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941806,0.0005636754,0.004612622,0.00003154508,0.00000821992,0.00001047594,0.000101256,0.00004857597,0.0004431412],"genre_scores_gemma":[0.9960101,0.0002380256,0.002537187,0.00003017922,0.000004982001,0.00001274217,0.0002597017,0.00002019622,0.0008869909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005083883,"threshold_uncertainty_score":0.001700759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06224052763795551,"score_gpt":0.3423607829822163,"score_spread":0.2801202553442608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}