{"id":"W2062161748","doi":"10.1016/j.freeradbiomed.2012.07.011","title":"Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment","year":2012,"lang":"en","type":"review","venue":"Free Radical Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":false,"ca_institutions":"CancerCare Manitoba; Research Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Oxidative stress; Reactive oxygen species; Cell biology; Carcinogenesis; Intracellular; Programmed cell death; Cancer cell; Biology; Downregulation and upregulation; Cancer; Chemistry; Biochemistry; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001625006,0.000271874,0.001725544,0.0002007583,0.00005074729,8.033883e-7,0.00009741773,0.0004334168,0.0003208165],"category_scores_gemma":[0.00009458288,0.0001623689,0.0001720755,0.0001786111,0.0005637452,0.00002227516,0.00002048082,0.0001526863,8.938508e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002524557,"about_ca_system_score_gemma":0.0003744212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003750907,"about_ca_topic_score_gemma":0.00009225323,"domain_scores_codex":[0.9987524,0.0000824355,0.0005335901,0.0003180109,0.00005757321,0.0002559646],"domain_scores_gemma":[0.9987602,0.0003700851,0.0002929954,0.0003418117,0.00005340675,0.000181484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001346614,0.0002109568,0.0009673553,0.002269165,0.0005860733,0.0000013433,0.0001413325,3.997434e-8,0.0002807031,0.008478309,0.0006771226,0.986253],"study_design_scores_gemma":[0.002312138,0.00068891,0.02687673,0.003308035,0.002463116,0.00002024135,0.00001002943,0.000001992761,0.00006920929,0.002143952,0.9619794,0.0001262673],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005588682,0.9943765,0.0000534916,0.002387769,0.0002555666,0.001459483,0.0005806228,0.00001874396,0.0003089929],"genre_scores_gemma":[0.001723223,0.9940465,0.00008471962,0.0001491271,0.001187098,0.00114608,0.0009586713,0.00002212479,0.0006824508],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9861267,"threshold_uncertainty_score":0.6621213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1124225018373505,"score_gpt":0.4353040711394259,"score_spread":0.3228815693020755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}