{"id":"W2062213647","doi":"10.1371/journal.ppat.1004396","title":"MHC Class II Restricted Innate-Like Double Negative T Cells Contribute to Optimal Primary and Secondary Immunity to Leishmania major","year":2014,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Manitoba Health Research Council","keywords":"Biology; Leishmania major; Immunology; CD8; Leishmania; Immunity; Cytotoxic T cell; Granzyme B; Effector; Innate immune system; Adoptive cell transfer; MHC class I; Granzyme; Cell biology; T cell; Immune system; In vitro; Perforin; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001196016,0.0005170736,0.0002239354,0.0001582766,0.00007547178,0.0002077981,0.0001295401,0.0002129564,0.001397556],"category_scores_gemma":[0.0001241851,0.0001166111,0.0001169876,0.00006304586,0.0001923456,0.0001868903,0.0002166397,0.0005340384,0.0004791625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008729398,"about_ca_system_score_gemma":0.0001404486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007683906,"about_ca_topic_score_gemma":0.0001419733,"domain_scores_codex":[0.99993,0.00001283034,0.000007384247,0.00001878013,0.00001018762,0.00002088212],"domain_scores_gemma":[0.9998554,0.00001542694,0.00004402055,0.00001263147,0.00001164467,0.00006087467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001403954,0.00002494282,0.0007493118,0.00006314106,0.000001894699,0.00008353591,0.00001511699,0.00003045102,0.9951178,0.00006296368,0.00002869488,0.003681781],"study_design_scores_gemma":[0.0001392486,0.003305991,0.04640804,0.00006649337,0.000128689,0.00534769,0.0002447397,0.001818272,0.9306743,0.0007838,0.01106695,0.00001587389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864817,0.00500172,0.005499238,0.0001101248,0.00004064287,0.00006800568,0.0001260756,0.0001121287,0.002560396],"genre_scores_gemma":[0.9939219,0.001579128,0.002274338,0.00007259352,0.00004691722,0.00003267295,0.0001336277,0.00001560463,0.001923215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001397556,"threshold_uncertainty_score":0.004675269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172628301617286,"score_gpt":0.2659735536016894,"score_spread":0.2442472705855166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}