{"id":"W2062237220","doi":"10.1016/j.bbrc.2013.12.019","title":"Altered expression of calcineurin, calpain, calpastatin and HMWCaMBP in cardiac cells following ischemia and reperfusion","year":2013,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"College of Pharmacy and Nutrition, University of Saskatchewan","keywords":"Calpain; Calpastatin; Calcineurin; Ischemia; Cell biology; Myocyte; Viability assay; Biology; Reperfusion injury; Programmed cell death; Andrology; Molecular biology; Cell; Medicine; Apoptosis; Transplantation; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003823266,0.0001136633,0.0001735555,0.00007182157,0.0001416294,0.00003045407,0.0001588314,0.0001505648,0.000005771847],"category_scores_gemma":[0.0002715472,0.00009338853,0.00005448324,0.0001699548,0.0004877469,0.00001204683,0.0006111645,0.00024593,0.000001954401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001188051,"about_ca_system_score_gemma":0.00003113258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002312905,"about_ca_topic_score_gemma":0.000005450199,"domain_scores_codex":[0.9987714,0.0002622501,0.0002343843,0.0003211949,0.0002002018,0.0002106081],"domain_scores_gemma":[0.9989651,0.0001686368,0.00004262631,0.0005167397,0.0001366565,0.0001702848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003704337,0.0001109389,0.001097138,0.00004388029,0.000007612728,1.662391e-7,0.00005418759,2.089434e-7,0.9944259,0.00007747774,0.00151164,0.002633786],"study_design_scores_gemma":[0.0003819409,0.0001290969,0.006621874,0.00007811548,0.000006438436,0.000001107288,0.0001699211,0.0006410243,0.9899305,0.0002101321,0.001713277,0.0001165728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969442,0.001574337,0.00005119517,0.0008844283,0.00001857831,0.0003921398,0.00001194986,0.000006692976,0.0001164682],"genre_scores_gemma":[0.9970595,0.001291206,0.001209471,0.00003677292,0.00005582251,0.00009021727,0.00007887004,0.00001064052,0.0001675272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005524735,"threshold_uncertainty_score":0.3808274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02655520570139956,"score_gpt":0.3207187251239224,"score_spread":0.2941635194225228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}