{"id":"W2062246641","doi":"10.1002/chem.201202528","title":"Highly Enantioselective Synthesis of 1,2,3‐Substituted Cyclopropanes by Using α‐Iodo‐ and α‐Chloromethylzinc Carbenoids","year":2012,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; Université de Montréal; Centre in Green Chemistry and Catalysis","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Electrophile; Enantioselective synthesis; Negishi coupling; Formal synthesis; Stereoselectivity; Chemistry; Lithium (medication); Stereochemistry; Combinatorial chemistry; Ligand (biochemistry); Organic chemistry; Catalysis; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000190543,0.0005193254,0.0002006601,0.0002552076,0.0001781296,0.0002828751,0.0003027254,0.0002490489,0.001476794],"category_scores_gemma":[0.0001675492,0.000172631,0.000199999,0.0002106618,0.0002229918,0.0002916524,0.0002856421,0.0005611941,0.0004290275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002270951,"about_ca_system_score_gemma":0.0004481186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004075022,"about_ca_topic_score_gemma":0.001018836,"domain_scores_codex":[0.9998928,0.00001749261,0.000009562772,0.00001858885,0.00002058244,0.00004089744],"domain_scores_gemma":[0.9999199,0.00001375126,0.00002841846,0.00001070188,0.000009211222,0.00001812123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000210743,0.00004894935,0.0002786962,0.0003399346,0.00001923003,0.0007389264,0.0001773027,0.0008117625,0.9859324,0.002486258,0.0003231413,0.008632691],"study_design_scores_gemma":[0.00005273616,0.0002900176,0.0006978691,0.00001841404,0.00002125858,0.0005557443,0.00005070987,0.000581825,0.9895314,0.0001714345,0.008009116,0.00001948451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562988,0.006020513,0.01482996,0.0003547537,0.0001400766,0.000146597,0.0007439746,0.0002136642,0.02125161],"genre_scores_gemma":[0.9868029,0.003235352,0.006564464,0.00008278294,0.00002409826,0.00005439185,0.0003110808,0.00003473517,0.00289021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001476794,"threshold_uncertainty_score":0.004940391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01385018132435821,"score_gpt":0.2212309089874924,"score_spread":0.2073807276631342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}