{"id":"W2062267059","doi":"10.1007/s003840050003","title":"Genetic testing and surgical decision making in hereditary colorectal cancer","year":2000,"lang":"en","type":"review","venue":"International Journal of Colorectal Disease","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Medicine; Genetic testing; Familial adenomatous polyposis; Lynch syndrome; Colorectal cancer; Genetic counseling; Hepatology; Adenomatous polyposis coli; Surgical oncology; Prophylactic Surgery; Cancer; Bioinformatics; General surgery; Internal medicine; Oncology; DNA mismatch repair; Genetics; Ovarian cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009808261,0.0005927873,0.001329178,0.001769989,0.0001794265,0.000678711,0.0007199119,0.001252537,0.001604335],"category_scores_gemma":[0.00317465,0.000194943,0.000472026,0.002376383,0.000528361,0.0008502825,0.0003517475,0.001138717,0.000374284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006956195,"about_ca_system_score_gemma":0.001257342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004004234,"about_ca_topic_score_gemma":0.006880327,"domain_scores_codex":[0.999627,0.0001415777,0.00004660308,0.00005110748,0.0001139139,0.00001979134],"domain_scores_gemma":[0.9979073,0.001634223,0.000197122,0.00001944772,0.0001885969,0.00005338875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001248908,0.00007696258,0.00203177,0.01242564,0.0002641295,0.0007754724,0.00006666746,0.0006426207,0.0002630034,0.002283448,0.02344864,0.9575968],"study_design_scores_gemma":[0.0002246587,0.0003826336,0.01900377,0.03502012,0.00172859,0.01224332,0.0004617473,0.0008784269,0.0005279261,0.00982649,0.9196039,0.00009835114],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001736349,0.9988325,0.00007566702,0.00039188,0.0001073479,0.000001413291,0.000005380089,0.000001674742,0.0004105054],"genre_scores_gemma":[0.001761296,0.9974213,0.000162701,0.0002269155,0.0002685177,0.000002512068,0.00001104105,3.664463e-7,0.0001453286],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004004234,"threshold_uncertainty_score":0.007961869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03546116574515885,"score_gpt":0.3744567453833143,"score_spread":0.3389955796381555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}