{"id":"W2062267059","doi":"10.1007/s003840050003","title":"Genetic testing and surgical decision making in hereditary colorectal cancer","year":2000,"lang":"en","type":"review","venue":"International Journal of Colorectal Disease","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Medicine; Genetic testing; Familial adenomatous polyposis; Lynch syndrome; Colorectal cancer; Genetic counseling; Hepatology; Adenomatous polyposis coli; Surgical oncology; Prophylactic Surgery; Cancer; Bioinformatics; General surgery; Internal medicine; Oncology; DNA mismatch repair; Genetics; Ovarian cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002855398,0.0004946423,0.001532743,0.0008390817,0.00004098922,0.00008394022,0.0004863997,0.0002824021,0.000720611],"category_scores_gemma":[0.0009515581,0.0004000582,0.0005656472,0.0004276144,0.0001752677,0.000125143,0.0001814644,0.0008899108,0.00001322096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009575831,"about_ca_system_score_gemma":0.002147361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000300279,"about_ca_topic_score_gemma":0.00003341407,"domain_scores_codex":[0.996307,0.0001657816,0.001497475,0.0004545198,0.001219123,0.0003561112],"domain_scores_gemma":[0.9968147,0.001339578,0.0007343757,0.0001347346,0.0004928326,0.0004837349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003356694,0.0002253903,0.01166177,0.001059283,0.0003604332,0.01349175,0.00003809734,0.0001207689,0.000002456123,0.000002060762,0.0002417965,0.9694395],"study_design_scores_gemma":[0.008220352,0.002411824,0.2586224,0.1760368,0.004590673,0.03663422,0.00003878953,0.00139212,0.000007815104,0.001264137,0.5089616,0.001819232],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2510542,0.7463088,0.000004423321,0.00004499088,0.001619712,0.0004960715,0.0001179628,0.00001423877,0.0003395734],"genre_scores_gemma":[0.1265752,0.8699437,0.001871855,0.00005938893,0.001370705,0.00007016098,0.00001282881,0.0000761961,0.00001992433],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9676203,"threshold_uncertainty_score":0.9998451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03546116574515885,"score_gpt":0.3744567453833143,"score_spread":0.3389955796381555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}