{"id":"W2062282550","doi":"10.3390/v2081752","title":"Hepatitis C Virus NS3/4A Protease Inhibitors: A Light at the End of the Tunnel","year":2010,"lang":"en","type":"article","venue":"Viruses","topic":"Hepatitis C virus research","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"","keywords":"NS3; Protease; Hepatitis C virus; Virology; Serine protease; NS2-3 protease; Drug discovery; Biology; Virus; Pharmacology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002393017,0.0003966032,0.0007010978,0.0004485567,0.0005694171,0.002254792,0.0005686293,0.001935164,0.004317569],"category_scores_gemma":[0.001745406,0.00025024,0.0003344558,0.0003731039,0.001186626,0.0048524,0.0008876735,0.003570928,0.001711196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000435567,"about_ca_system_score_gemma":0.001097575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003008394,"about_ca_topic_score_gemma":0.001084531,"domain_scores_codex":[0.9994295,0.0001699579,0.00004555883,0.00004056904,0.0002354374,0.00007898299],"domain_scores_gemma":[0.99892,0.0004031717,0.0001050829,0.00005397264,0.0002892988,0.0002286197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001397368,0.0002809932,0.0007516768,0.002525884,0.0000576238,0.00104715,0.0005452333,0.0007605584,0.01924122,0.07620261,0.1611314,0.7360582],"study_design_scores_gemma":[0.0002446565,0.001340204,0.0007658539,0.0009387842,0.00002686248,0.001394853,0.0003085581,0.0004393079,0.002852379,0.02306251,0.9685814,0.00004477817],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01459651,0.8543809,0.004434329,0.09991222,0.00908054,0.00006280241,0.0001336966,0.0002774217,0.01712157],"genre_scores_gemma":[0.08647906,0.8215832,0.006973307,0.04320196,0.01028132,0.00007589174,0.0001882735,0.0001005716,0.0311164],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004317569,"threshold_uncertainty_score":0.01444376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505037604613219,"score_gpt":0.3014884581509131,"score_spread":0.2764380821047809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}