{"id":"W2062389087","doi":"10.1101/pdb.prot5011","title":"Construction and Characterization of Adenovirus Vectors","year":2009,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; ALS Society of Canada","keywords":"Transduction (biophysics); Transgene; Plasmid; Biology; Gene delivery; Vector (molecular biology); Cloning (programming); Gene; Genetic enhancement; Computational biology; Viral vector; In vivo; Transfection; Genome; Cloning vector; Genetics; Recombinant DNA; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002108696,0.0008357642,0.0009311953,0.001702944,0.0007174586,0.001360407,0.001069475,0.0005353318,0.003512947],"category_scores_gemma":[0.002094103,0.0006027915,0.0005405425,0.001157772,0.0005128471,0.0005688936,0.0003983684,0.001437653,0.004299945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007869566,"about_ca_system_score_gemma":0.0009644088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007270015,"about_ca_topic_score_gemma":0.0008668028,"domain_scores_codex":[0.9984013,0.0002882062,0.0003606596,0.0002129323,0.000551263,0.0001855533],"domain_scores_gemma":[0.9987293,0.0003600237,0.0001389125,0.0002285148,0.0003958161,0.0001473063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003702778,0.0002765562,0.001248957,0.00129928,0.0000438079,0.000357116,0.0002994789,0.001375108,0.9376978,0.004307445,0.002521151,0.05020309],"study_design_scores_gemma":[0.00006614762,0.0006451837,0.002458114,0.0001437951,0.00005086963,0.0007720228,0.0001316492,0.002278891,0.8194327,0.0010219,0.172949,0.00004965959],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3280537,0.02515336,0.5449877,0.001417791,0.001157736,0.01248046,0.05146655,0.002627894,0.03265487],"genre_scores_gemma":[0.3343762,0.0269599,0.5062234,0.000418406,0.0002385138,0.006833718,0.09325578,0.0008542014,0.03083984],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003512947,"threshold_uncertainty_score":0.01175201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600136121852969,"score_gpt":0.2933106057832059,"score_spread":0.2773092445646762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}