{"id":"W2062389412","doi":"10.1002/jcb.10562","title":"Adenosine inhibits activation‐induced T cell expression of CD2 and CD28 co‐stimulatory molecules: Role of interleukin‐2 and cyclic AMP signaling pathways","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Adenosine; CD28; Adenylyl cyclase; T cell; Signal transduction; Chemistry; Cell biology; Intracellular; Adenosine A2B receptor; IL-2 receptor; Adenosine receptor; Biology; Molecular biology; Receptor; Biochemistry; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002923553,0.0002113914,0.0003307575,0.0000820688,0.00004774603,0.00001478358,0.0001401923,0.0002527626,0.00001934099],"category_scores_gemma":[0.0001479818,0.0001960474,0.000121082,0.0000846836,0.00009816557,0.00001308773,0.00006569436,0.0002001636,2.363369e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001299234,"about_ca_system_score_gemma":0.0001261387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002128173,"about_ca_topic_score_gemma":4.225319e-8,"domain_scores_codex":[0.9986687,0.00007006721,0.0006161118,0.0002327801,0.0002418743,0.000170494],"domain_scores_gemma":[0.9986104,0.00003951222,0.0007645967,0.0002161403,0.0002316118,0.0001376739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001205385,0.0001168636,0.0009903773,0.0001873874,0.00004302198,0.000005074254,0.0001532176,0.0001219574,0.9980356,0.000005468463,0.0001497836,0.00007069789],"study_design_scores_gemma":[0.000992526,0.0002423357,0.00004435155,0.0002679297,0.00004709562,0.00006552297,0.0004597609,0.00001567925,0.9973853,0.00006883455,0.0002268754,0.0001837729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872243,0.01027497,0.00207091,0.000008709782,0.00003061911,0.00006703192,0.000007958739,0.000002740615,0.0003127541],"genre_scores_gemma":[0.9983439,0.0001639491,0.001230996,0.00002607156,0.0001322448,0.000001284153,0.00002326913,0.00002591383,0.0000523324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01111963,"threshold_uncertainty_score":0.7994583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009276425159811549,"score_gpt":0.2216834429442377,"score_spread":0.2124070177844261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}