{"id":"W2062429356","doi":"10.2174/138945011794815310","title":"Proteases of Porphyromonas gingivalis as Important Virulence Factors in Periodontal Disease and Potential Targets for Plant-Derived Compounds: A Review Article","year":2011,"lang":"en","type":"review","venue":"Current Drug Targets","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Porphyromonas gingivalis; Proteases; Microbiology; Protease; Aminopeptidase; Chronic periodontitis; Virulence; Biology; Periodontitis; Periodontal pathogen; Proteolytic enzymes; Enzyme; Biochemistry; Bacteria; Medicine; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003810089,0.000713828,0.0009598347,0.002511768,0.0002817237,0.001130654,0.0004574722,0.001249524,0.002435204],"category_scores_gemma":[0.0003634035,0.0001851239,0.0004577569,0.002624736,0.0003351251,0.001265034,0.0004624224,0.001086251,0.0007171687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004793653,"about_ca_system_score_gemma":0.0008459178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007697032,"about_ca_topic_score_gemma":0.001061684,"domain_scores_codex":[0.9998413,0.00002390651,0.00002602725,0.0000351601,0.0000532785,0.00002030173],"domain_scores_gemma":[0.9997398,0.0001019164,0.00005382062,0.000004761433,0.00007195582,0.00002761137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002507891,0.000209437,0.0007182785,0.03974443,0.0001648893,0.001044893,0.0002875942,0.0004816654,0.01218622,0.003965357,0.03334277,0.9076036],"study_design_scores_gemma":[0.00002762731,0.0003994134,0.002420327,0.004143637,0.0002759507,0.006006889,0.0002374913,0.0002365444,0.002243725,0.001523703,0.9824466,0.00003818176],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002496126,0.9990389,0.00007874909,0.0001542837,0.0001422803,0.000002208626,0.000007467616,0.000002622727,0.0003238673],"genre_scores_gemma":[0.001356535,0.9975603,0.0001470413,0.0001193389,0.0003351229,0.00000393331,0.00002052246,8.580409e-7,0.000456405],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002511768,"threshold_uncertainty_score":0.008146584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05662665815220201,"score_gpt":0.3509446507243881,"score_spread":0.2943179925721861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}