{"id":"W2062457363","doi":"10.1016/s1873-9946(12)60505-4","title":"The future of inflammatory bowel disease management: Combining progress in trial design with advances in targeted therapy","year":2012,"lang":"en","type":"review","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Abbott Fund","keywords":"Medicine; Crohn's disease; Disease; Placebo; Clinical trial; Inflammatory bowel disease; Population; Intensive care medicine; Randomized controlled trial; Internal medicine; Surgery; Oncology; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02572948,0.001162608,0.004137309,0.001924507,0.0002870272,0.002968484,0.002642545,0.00312936,0.002764813],"category_scores_gemma":[0.02672349,0.0004515994,0.001476503,0.002142989,0.002053879,0.004117773,0.001243213,0.004246647,0.0009067968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001859474,"about_ca_system_score_gemma":0.00433524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008001156,"about_ca_topic_score_gemma":0.001359695,"domain_scores_codex":[0.991552,0.00585845,0.0006773868,0.0004295445,0.001294767,0.000187856],"domain_scores_gemma":[0.9746819,0.02108969,0.00126991,0.0004931175,0.001872974,0.0005924705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004971675,0.00006776518,0.0002053243,0.01727306,0.0003993811,0.00008738218,0.00005153336,0.0004930616,0.0002695434,0.006661369,0.01462467,0.9593698],"study_design_scores_gemma":[0.002523602,0.001476033,0.00371054,0.08349515,0.002372857,0.001886809,0.0003321494,0.001970562,0.0006520251,0.06398452,0.8374361,0.0001595765],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006471432,0.9970164,0.00055478,0.001794479,0.0003180069,0.00001815175,0.000006273795,0.00000721377,0.0002198865],"genre_scores_gemma":[0.001632647,0.9928535,0.002249644,0.00179557,0.001129182,0.00009362873,0.00001984453,0.000006817877,0.0002192121],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02572948,"threshold_uncertainty_score":0.1360721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0114894045991111,"score_gpt":0.2735580770297443,"score_spread":0.2620686724306333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}