{"id":"W2062511665","doi":"10.1371/journal.pone.0071882","title":"Amelioration of Murine Passive Immune Thrombocytopenia by IVIg and a Therapeutic Monoclonal CD44 Antibody Does Not Require the Myd88 Signaling Pathway","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canadian Blood Services; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Government of Canada; Australian Government","keywords":"Immunology; Antibody; TLR3; TLR2; Immune system; TLR4; Medicine; Acquired immune system; Platelet; Receptor; Innate immune system; Toll-like receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417764,0.0006829987,0.0004909592,0.0006488601,0.000199847,0.0003019106,0.0004518972,0.0007983677,0.00131152],"category_scores_gemma":[0.000149514,0.0002396882,0.0004830044,0.0002215714,0.0003248221,0.0003523286,0.0001987862,0.001793461,0.0003882445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003602308,"about_ca_system_score_gemma":0.0003594662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007287293,"about_ca_topic_score_gemma":0.0009971102,"domain_scores_codex":[0.9996477,0.00005485186,0.00003889564,0.00005303987,0.00008515309,0.0001203468],"domain_scores_gemma":[0.9997559,0.0000300403,0.00008356674,0.0000294781,0.00002403962,0.00007689782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000622092,0.0004729241,0.0001790546,0.00007038283,0.00001738504,0.0001252487,0.00002913808,0.0001800341,0.9956071,0.0002267101,0.0001133264,0.00235665],"study_design_scores_gemma":[0.0001747924,0.004297863,0.003751677,0.00002262183,0.00004971055,0.000454453,0.00003862736,0.001889175,0.9863732,0.0001044143,0.002834613,0.000008694667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926682,0.001304854,0.00254946,0.0002482846,0.00008533065,0.00008164179,0.0006639207,0.0002254974,0.002172908],"genre_scores_gemma":[0.9902143,0.001076549,0.002511934,0.000164417,0.00003431118,0.0001259918,0.001083868,0.00004236129,0.004746112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00131152,"threshold_uncertainty_score":0.004387438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02715755179627634,"score_gpt":0.2524144138844758,"score_spread":0.2252568620881995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}