{"id":"W2062718003","doi":"10.1016/j.bbmt.2014.06.019","title":"Outcomes after Hematopoietic Stem Cell Transplantation for Children with I-Cell Disease","year":2014,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; BC Children's Hospital; University of British Columbia","funders":"National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Terumo BCT; Health Resources and Services Administration; Medac; Swedish Orphan Biovitrum; Otsuka America; Incyte; Genentech; Seattle Genetics; Chimerix; Medical College of Wisconsin; Blue Cross and Blue Shield Association; Takeda Oncology; University of Minnesota; Kiadis Pharma; Sigma-Tau Pharmaceuticals; Therakos; StemCyte; Tarix Pharmaceuticals; University of Utah; HistoGenetics; WellPoint; Teva Pharmaceutical Industries; National Marrow Donor Program; St. Baldrick's Foundation; National Institute of Allergy and Infectious Diseases; Roswell Park Cancer Institute; Fred Hutchinson Cancer Research Center; Health Research; U.S. Navy; Celgene; Osiris Therapeutics; Merck; GlaxoSmithKline; Leukemia and Lymphoma Society; Be The Match Foundation; Allos Therapeutics; Actinium Pharmaceuticals; Ariad Pharmaceuticals; Otsuka America Pharmaceutical; Amgen; Onyx Pharmaceuticals; U.S. Department of Defense; Sanofi","keywords":"Medicine; Hematopoietic stem cell transplantation; Disease; Stem cell; Transplantation; Lysosomal storage disease; Hematopoietic stem cell; Cause of death; Haematopoiesis; Pediatrics; Intensive care medicine; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087722,0.0001399149,0.0002540735,0.00009205782,0.00004677442,0.000005753422,0.00004596733,0.000086511,0.00001325351],"category_scores_gemma":[0.000002654988,0.0001027537,0.00006505894,0.00004599319,0.0001084991,0.00005348686,0.000002590486,0.0000639073,0.000001905955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003652436,"about_ca_system_score_gemma":0.0000354342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002491813,"about_ca_topic_score_gemma":0.00002718405,"domain_scores_codex":[0.9992073,0.00005395052,0.0001927956,0.0002488531,0.0001104016,0.0001867686],"domain_scores_gemma":[0.9995583,0.00009559206,0.00006129273,0.0001107797,0.00005637282,0.0001176044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00335709,0.0003291152,0.9476941,0.002664864,0.0001028153,0.00001195167,0.0008924511,0.000003150527,0.04296605,0.0001298806,0.000006223809,0.00184234],"study_design_scores_gemma":[0.01224669,0.001372035,0.9190583,0.000125387,0.001753406,0.00007506194,0.00006836592,0.00003516115,0.06483208,0.0001828109,0.00002603409,0.0002247115],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920232,0.0005903036,0.006074886,0.0002291994,0.00002219208,0.0007232059,0.0001789076,0.00002491147,0.0001331762],"genre_scores_gemma":[0.9979386,0.0005438302,0.0006741728,0.0001022483,0.0000210868,0.0001051165,0.0004737703,0.00001778939,0.0001234269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02863581,"threshold_uncertainty_score":0.4190174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007750355377629409,"score_gpt":0.2396496988129569,"score_spread":0.2318993434353274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}