{"id":"W2062746072","doi":"10.1021/bi201054x","title":"Identification of Calcium-Independent and Calcium-Enhanced Binding between S100B and the Dopamine D2 Receptor","year":2011,"lang":"en","type":"article","venue":"Biochemistry","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Calcium; Chemistry; Biophysics; Calcium-binding protein; Biochemistry; Binding site; Receptor; Calcium in biology; EF hand; Dopamine; Biology; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001076361,0.0002218333,0.0003285313,0.0001830549,0.0001241836,0.0001789679,0.0002520091,0.0003827601,0.001091492],"category_scores_gemma":[0.000192043,0.0001563212,0.0003224798,0.0001421564,0.0001406212,0.00008723698,0.0002294026,0.0003806037,0.0003654839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004383332,"about_ca_system_score_gemma":0.0001419952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001218403,"about_ca_topic_score_gemma":0.00198299,"domain_scores_codex":[0.999886,0.00001552149,0.000005999011,0.00002196412,0.00004264715,0.00002785521],"domain_scores_gemma":[0.9999127,0.00001569836,0.00001964685,0.00000791111,0.00001109583,0.00003283454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008625018,0.00001266376,0.0003257775,0.00001372617,0.000005142471,0.00005927984,0.000007968142,0.00003298278,0.9990267,0.00001791533,0.000021584,0.0003900213],"study_design_scores_gemma":[0.00005033645,0.0002560361,0.03186528,0.00001020874,0.00001772579,0.0009208315,0.00005786942,0.004857596,0.9598609,0.00006191478,0.002028432,0.00001296751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982717,0.0003294225,0.0008513134,0.00004022027,0.000004464782,0.00001409244,0.0001112308,0.00001361468,0.0003638956],"genre_scores_gemma":[0.9945934,0.0002226119,0.003150511,0.00010776,0.000004992497,0.00002178589,0.0005197979,0.00001148792,0.001367648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001218403,"threshold_uncertainty_score":0.003651381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0218998654716898,"score_gpt":0.255894169845054,"score_spread":0.2339943043733642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}