{"id":"W2062746072","doi":"10.1021/bi201054x","title":"Identification of Calcium-Independent and Calcium-Enhanced Binding between S100B and the Dopamine D2 Receptor","year":2011,"lang":"en","type":"article","venue":"Biochemistry","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Calcium; Chemistry; Biophysics; Calcium-binding protein; Biochemistry; Binding site; Receptor; Calcium in biology; EF hand; Dopamine; Biology; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002943715,0.0001412045,0.0001624941,0.00001975299,0.0000843219,0.00001925532,0.0001583563,0.000168543,0.0000222714],"category_scores_gemma":[0.00008765192,0.000107912,0.00005497668,0.00005876882,0.0003007268,0.000004346854,0.0001421414,0.00008301566,0.000002829972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007841015,"about_ca_system_score_gemma":0.00003029585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003585764,"about_ca_topic_score_gemma":0.000001716584,"domain_scores_codex":[0.9991015,0.00003191163,0.000272665,0.0003241288,0.000110558,0.0001592605],"domain_scores_gemma":[0.9993607,0.00001417312,0.0001700069,0.0003158277,0.00006669191,0.00007255995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008652015,0.00002198819,0.002540867,0.00005315901,0.00004427588,3.223384e-7,0.00008932666,5.820059e-8,0.9956424,0.00004048611,0.00008421315,0.001396334],"study_design_scores_gemma":[0.0007860554,0.00004991031,0.003558252,0.00002140193,0.00003140868,0.000005147983,0.0002174564,0.000005854091,0.9949043,0.00003384009,0.0002509169,0.0001354388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971231,0.0009136568,0.001031711,0.00005307744,0.00004879362,0.0001688257,0.00005199921,0.000008739976,0.0006000446],"genre_scores_gemma":[0.9984847,0.0001438782,0.0001605446,0.0000197793,0.0001820855,0.00002569857,0.00007057355,0.0000149719,0.0008977805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001361536,"threshold_uncertainty_score":0.4400522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0218998654716898,"score_gpt":0.255894169845054,"score_spread":0.2339943043733642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}